Chimerix Investor Conference Presentation Deck
Patient Demographics and Disease Characteristics
Age (years), median (range)
<18 years, N(%)
18 - <40 years, N(%)
>40 years, N(%)
Gender, N(%)
Male
Female
Race, N(%)
White
Other
Black
Asian
Not reported
Body weight (kg), median (range)
Performance status (KPS/LPS), N(%)
60-70
80
90-100
10
N=50
30 (870)
4 (8%)
32 (64%)
14 (28%)
27 (54%)
23 (46%)
39 (78%)
6 (12%)
3 (6%)
1 (2%)
1 (2%)
88 (29 - 199)
14 (28%)
20 (40%)
16 (32%)
¹Multifocal disease includes non-target lesions
²Sum of product of diameters of enhancing target lesions per BICR
Primary tumor location, N(%)
Thalamic
Other midline
Multifocal disease¹, N(%)
>1 Target lesion, N(%)
Tumor size² (cm2), median (range)
H3 K27M detection method
IHC, N(%)
NGS, N(%)
First recurrence, N(%)
Prior temozolomide, N(%)
Time from recurrence, days, median (range)
Time from prior radiation, months, median
(range)
Time from initial diagnosis, months, median
(range)
Daily steroid dose (mg, dex equiv): median
(range)
N=50
33 (66%)
17 (34%)
23 (46%)
9 (18%)
10.4 (1.640.8)
47 (94%)
3 (6%)
37 (74%)
44 (88%)
20 (1 126)
7.5 (3104)
10.9 (5-105)
1.1 (0.0 12.0)View entire presentation