OmniAb Investor Conference Presentation Deck

Host Antibody Repertoires NUMEROUS OPTIONS AVAILABLE TO ADDRESS DIVERSE PARTNER OBJECTIVES OmniMouse OmniRat niR OmniChicken OmniFlic OmniClic OmniTaur ● ● ● ● ● ● ● ● ● ● ● V genes Full human V gene diversity Choice of light chain isotype Full human V gene diversity Choice of light chain isotype Single framework VH3/VK3 or VH3/VL1 Full human VH gene diversity with non-diversifying VK3 Single framework VH3/non-diversifying VK3 Single framework VH4/VL1 ● ● Structural and immunological features Diverse V gene usage and mixed genetic backgrounds Diverse V gene usage and mixed genetic backgrounds Distinctive target recognition Create Diverse Antibody Pools Evolutionarily divergent host system for robust immune responses Fixed light chain for bispecific applications • Fixed light chain for bispecific applications Ultralong CDR-H3's for enormous structural diversity ● ● ● ● ● ● ● ● ● ● Screen Antibody Candidates ● Identify the Right Antibody Benefits for therapeutics discovery and development Widely accessible and flexible workflows Industry standard Widely accessible and flexible workflows Extensive track record Diverse and new epitope coverage High homology targets Excellent physical properties Bispecific applications leveraging standard IgG format Diverse epitope coverage Excellent physical properties Ease of manufacturing Access cryptic epitopes Unique modalities (Picobodies™M) Building blocks for multispecific molecules 14 OmniAb

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