AstraZeneca Results Presentation Deck slide image

AstraZeneca Results Presentation Deck

BioPharmaceuticals: Cardiovascular, Renal and Metabolism Total Revenue $6.0bn; growth +10% Farxiga: 51% growth to $2.1bn Strong momentum continues, fastest growing SGLT2i globally 22 $m 900 800 700 600 500 400 300 200 100 0 Q4 2019 Q1 Q2 Q3 2020 US Europe EROW EM Q4 Q1. Q2 2021 Q3 • US +31%, Europe +50% and EMS +74%, boosted by HF and CKD launches • CKD approval in Europe and Japan obtained in the quarter Updated ESC guidelines now recommend Farxiga as 1st-line treatment for HFrEF Forxiga #1 innovative anti-diabetic in China and Brazil US branded K+ binder TRX share¹ Branded leadership extended in the US 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Jul 2019 Sep 2019 Lokelma Nov 2019 SGLT2i = Sodium-glucose transport protein 2 inhibitor; HFrEF = Heart failure with reduced ejection fraction; K+ = potassium; TRx = total prescriptions. 1. IQVIA US monthly total prescription share data Jan 2020 Mar 2020 May 2020 Lokelma Branded competitor Jul 2020 Sep 2020 Nov 2020 Jan 2021 Mar 2021 May 2021 Jul 2021 Volume growth US and Japan, Europe benefitting from new launches Sep 2021 ESC guidelines now recommend novel K+ binders to manage hyperkalaemia 58% B
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