AstraZeneca Results Presentation Deck slide image

AstraZeneca Results Presentation Deck

Calquence and Enhertu Strong launch trajectories continue 17 $m 400 350 300 250 200 150 100 50 0 Calquence: 146% growth to $843m Approvals/Reimbursements: 70/20 (CLL), 34/13 (MCL) Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 2019 2020 US Europe EROW EM 2021 • Global $843m; US $752m • US CLL New patient share of 52% in 1st- line BTKI class and 20% overall ¹ ● Global CLL Germany and UK largest growth contributors. Successful launches inc. France and Spain • US MCL Preferred BTKI in relapsed refractory MCL Se M CALQUENCE Watendinte caps 100 mg Am $m 80 60 40 20 0 Enhertu: 134% growth to $147m Approvals/Reimbursements: 9/4 (BC), 4/2 (GC) Q1 Q2 Q3 Q4 2020 US Europe EROW EM Q1 Q2 2021 CLL = chronic lymphocytic leukaemia; MCL = mantle cell lymphoma; BTKI = Bruton tyrosine kinase inhibitor; GC = gastric cancer; 3L = 3rd-line. 1. IQVIA US ALPD Claims data NPS data to Sep-21. Q3 ● ● Total revenue: Global $147m; US $120m Total in-market sales ex-Japan: $293m • US #1 in 3rd-line HER2+ breast cancer, strong launch in 2nd-line gastric cancer Global Strong launch in France continues #1 in all countries launched in 3L HER2+ mBC ENHERTU (am rasturnab denotecan-mok) For Injection 100 mg per vial For en ny P Perry CATORN KEEP REFRIGERATED THE gam Daichi Sankyo AdtraZeneca
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