Chimerix Investor Conference Presentation Deck
Overall Response Rate (RANO-LGG)
RANO-LGG¹
ORR (CR + PR + MR)
Complete Response (CR)
Partial Response (PR)
Minor Response (MR)
Stable Disease (SD)
Not Evaluable (NE)
Progressive Disease (PD)
Not Applicable (NA)
Disease Control Rate (CR + PR + MR + SD)
N=50
13 (26%)
95% CI: 15 - 40%
0 (0%)
6 (12%)
7 (14%)
8 (16%)
11 (22%)²
14 (28%)
4 (8%)³
21 (42%)
95% CI: 28 - 57%
30.0% (95% CI: 17.9 - 44.6%) achieved an objective
response by RANO-HGG and/or RANO-LGG criteria
¹ Integrated RANO LGG criteria assessment by dual reader BICR
2Eight overall radiographic SD accompanied by increase in corticosteroids; 3 overall radiographic PD accompanied by decrease in corticosteroids
16 ³Three patients did not have on-treatment monotherapy MRIs available for BICR; one patient censored prior to first on-treatment MRIView entire presentation