#1AMD FOURTH QUARTER AND FULL YEAR 2021 FINANCIAL RESULTS FEBRUARY 1, 2022#22 CAUTIONARY STATEMENT This presentation contains forward-looking statements concerning Advanced Micro Devices, Inc. (AMD) such as the features, functionality, performance, availability, timing and expected benefits of AMD products; AMD's expected first quarter 2022 and fiscal 2022 financial outlook, including revenue non-GAAP gross margin, non-GAAP operating expenses, non-GAAP operating expenses as a percentage of revenue, non-GAAP interest expense, taxes and other, non-GAAP tax rates and diluted share count; and the expected timing of the close of the Xilinx, Inc. transaction, which are made pursuant to the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are commonly identified by words such as "would," "may," "expects," "believes," "plans," "intends," "projects" and other terms with similar meaning. Investors are cautioned that the forward-looking statements in this presentation are based on current beliefs, assumptions and expectations, speak only as of the date of this presentation and involve risks and uncertainties that could cause actual results to differ materially from current expectations. Such statements are subject to certain known and unknown risks and uncertainties, many of which are difficult to predict and generally beyond AMD's control, that could cause actual results and other future events to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. Material factors that could cause actual results to differ materially from current expectations include, without limitation, the following: Intel Corporation's dominance of the microprocessor market and its aggressive business practices; global economic uncertainty; loss of a significant customer; impact of the COVID-19 pandemic on AMD's business, financial condition and results of operations; competitive markets in which AMD's products are sold; market conditions of the industries in which AMD products are sold; cyclical nature of the semiconductor industry; quarterly and seasonal sales patterns; AMD's ability to adequately protect its technology or other intellectual property; unfavorable currency exchange rate fluctuations; ability of third party manufacturers manufacture AMD's products on a timely basis in sufficient quantities and using competitive technologies; availability of essential equipment, materials, substrates or manufacturing processes; ability to achieve expected manufacturing yields for AMD's products; AMD's ability to introduce products on a timely basis with expected features and performance levels; AMD's ability to generate revenue from its semi-custom SoC products; potential security vulnerabilities; potential security incidents including IT outages, data loss, data breaches and cyber-attacks; uncertainties involving the ordering and shipment of AMD's products; AMD's reliance on third-party intellectual property to design and introduce new products in a timely manner; AMD's reliance on third-party companies for design, manufacture and supply of motherboards, software and other computer platform components; AMD's reliance on Microsoft and other software vendors' support to design and develop software to run on AMD's products; AMD's reliance on third-party distributors and add-in-board partners; impact of modification or interruption of AMD's internal business processes and information systems; compatibility of AMD's products with some or all industry-standard software and hardware; costs related to defective products; efficiency of AMD's supply chain; AMD's ability to rely on third party supply-chain logistics functions; AMD's ability to effectively control sales of its products on the gray market; impact of government actions and regulations such as export administration regulations, tariffs and trade protection measures; AMD's ability to realize its deferred tax assets; potential tax liabilities; current and future claims and litigation; impact of environmental laws, conflict minerals-related provisions and other laws or regulations; impact of acquisitions, joint ventures and/or investments on AMD's business, including the announced acquisition of Xilinx, and ability to integrate acquired businesses; AMD's ability to complete the Xilinx merger; impact of the announcement and pendency of the Xilinx merger on AMD's business; impact of any impairment of the combined company's assets on the combined company's financial position and results of operation; restrictions imposed by agreements governing AMD's notes and the revolving credit facility; AMD's indebtedness; AMD's ability to generate sufficient cash to meet its working capital requirements or generate sufficient revenue and operating cash flow to make all of its planned R&D or strategic investments; political, legal, economic risks and natural disasters; future impairments of goodwill and technology license purchases; AMD's ability to attract and retain qualified personnel; AMD's stock price volatility; and worldwide political conditions. Investors are urged to review in detail the risks and uncertainties in AMD's Securities and Exchange Commission filings, including but not limited to AMD's most recent reports on Forms 10-K and 10-Q. NON-GAAP FINANCIAL MEASURES In this presentation, in addition to GAAP financial results, AMD has provided non-GAAP financial measures including non-GAAP gross profit, non-GAAP operating expenses, non-GAAP operating income, non-GAAP net income, non-GAAP earnings per share and free cash flow. AMD uses a normalized tax rate in its computation of the non-GAAP income tax provision to provide better consistency across the reporting periods. For full year 2021, AMD uses a non-GAAP tax rate of 15%, which excludes the tax impact of pre-tax non-GAAP adjustments. For full year 2022, AMD uses a projected non-GAAP tax rate of 15%, which excludes the tax impact of pre- tax non-GAAP adjustments, reflecting currently available information, and a projected cash tax rate of approximately 9% that includes the projected current income tax liability plus known foreign withholding tax obligations paid expressed as a percentage of non-GAAP profit before tax. AMD is providing these financial measures because it believes this non-GAAP presentation makes it easier for investors to compare its operating results for current and historical periods and also because AMD believes it assists investors in comparing AMD's performance across reporting periods on a consistent basis by excluding items that it does not believe are indicative of its core operating performance. The non-GAAP financial measures disclosed in this presentation should be viewed in addition to and not as a substitute for or superior to AMD's reported results prepared in accordance with GAAP and should be read only in conjunction with AMD's Consolidated Financial Statements prepared in accordance with GAAP. These non-GAAP financial measures referenced are reconciled to their most directly comparable GAAP financial measures in the Appendices at the end of this presentation. This presentation also contains forward-looking non-GAAP measures concerning AMD's financial outlook such as gross margin, operating expenses, interest expense, taxes and other. These forward-looking non-GAAP measures are based on current expectations as of February 1, 2022, and assumptions and beliefs that involve numerous risks and uncertainties. AMD undertakes no intent or obligation to publicly update or revise its forward-looking statements made in this presentation except as may be required by law. Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 AMD#33 Best Product Portfolio in History AMD OUR JOURNEY Expanding Customer & Partner Ecosystem Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Significant Business Acceleration Best-in-Class Financial Performance AMD#44 ZEN OUR LEADERSHIP TECHNOLOGY AMD RDNA 2 AMD CDNA 2 INDUSTRY LEADING IP Executing Multi-generational CPU and GPU Products & Roadmaps. Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 ar KA THE 5-7 ADVANCED TECHNOLOGY Leadership Process Technology and 3D Chiplet Packaging gna feder HAL DATA CENTER LEADERSHIP Driving Innovation in Cloud, Enterprise and Accelerated Computing PC/GAMING SOLUTIONS Delivering Robust PC Experiences and Gaming Solutions. AMD#55 OUR BEST EVER PRODUCT PORTFOLIO 2 *************** AMD RYZEN 6000 SERIES 1111111ml..! I ftalall111111 AMD RYZEN Leadership desktop and mobile performance and advanced battery life AMDE EPYC ENTENT MAre AMD EPYC 3rd Gen AMD EPYC TM CPUs extend performance and TCO advantages Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 1.11 AMD RADEON Performance and power efficiency with AMD RDNA ™M 2 Architecture AMD INSTINCT AMD INSTINCT Heterogenous computing re-imagined for the exascale era with AMD CDNATM 2 Architecture PERFORMANCE LEADERSHIP IN PCs, DATA CENTER AND GAMING SEMI-CUSTOM Latest game consoles powered by "Zen" and AMD RDNA Architectures See endnotes R5K-002 and CZM-35 AMD#66 ■ Record revenue $16.4 billion, up 68% from 2020 ▪ Gross margin of 48% up 370 bps from prior year Significant growth in profitability Operating income $3.6 billion; Non-GAAP operating income $4.1 billion Operating margin 22%; Non-GAAP operating margin 25% Net income $3.2 billion; Non-GAAP net income $3.4 billion Diluted EPS $2.57; Non-GAAP diluted EPS $2.79 Operating cash flow $3.5 billion, up 229% y/y ▪ Record free cash flow of $3.2 billion, up 314% y/y $1 billion in strategic investments in long-term supply chain capacity Repurchased $1.8 billion of common stock ■ ● ● ● FINANCIAL SUMMARY FY 2021 ● Strong balance sheet with $3.6 billion in cash, cash equivalents and short-term investments Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 1. 1 Annual Revenue ($B) $9.8 FY 2020 +68% y/y $16.4 FY 2021 See Appendices for GAAP to Non-GAAP reconciliation AMD#7Record revenue $4.8 billion, up 49% y/y and 12% q/q ▪ Gross margin 50%, up 560 bps y/y and up 190 bps q/q OpEx $1.2 billion; Non-GAAP OpEx $1.1 billion ■ ■ ■ Strong quarterly profitability Operating income $1.2 billion; Non-GAAP operating income $1.3 billion ● QUARTERLY SUMMARY Q4 2021¹ ● Operating margin 25%; Non-GAAP operating margin 27% Net income $974 million; Non-GAAP net income $1.1 billion Diluted EPS $0.80; Non-GAAP diluted EPS $0.92 Operating cash flow $822 million, up 48% y/y Free cash flow of $736 million, up 53% y/y Repurchased $756 million of common stock ● ● 7 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 1. Quarterly Revenue ($B) $3.2 Q4 2020 +49% y/y $4.8 Q4 2021 See Appendices for GAAP to Non-GAAP reconciliation. AMD#88 COMPUTING AND GRAPHICS SEGMENT Q4 2021 ▪ Revenue $2.6 billion Up 32% y/y and 8% q/q driven by RyzenTM and RadeonTM processor sales ■ ■ ■ ● Higher Average Selling Prices (ASP) Client processor ASP grew y/y and q/q due to a richer mix of Ryzen processor sales GPU ASP increased y/y primarily driven by Radeon product sales; decreased q/q due to product mix Operating Income Operating income $566 million compared to $420 million a year ago and $513 million in the prior quarter Up y/y and q/q primarily driven by higher revenue, partially offset by higher operating expenses ● Strategic news and highlights Strong demand for premium desktop and notebook PCs built with Ryzen 5000 processors • Announced Ryzen processors with AMD 3D V-CacheTM technology to power incredible gaming experiences • Launched "Zen 3+" Ryzen 6000 notebook CPUs at CES 2022 featuring Ryzen CPUs, Radeon GPUs and Radeon software ● Updated the Radeon 6000 Series lineup featuring AMD RDNATM 2 to include new mobile and desktop platforms Previewed Ryzen 7000 Series desktop processors coming in 2H 2022 based on 5nm "Zen 4" architecture ● Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 AMD#99 ▪ Revenue $2.2 billion Up 75% y/y and 17% q/q driven by higher EPYCTM and semi-custom processor sales ● Higher Operating Income Operating income $762 million compared to $243 million a year ago and $542 million in the prior quarter Up y/y and q/q primarily driven by higher revenue and richer product mix, partially offset by higher operating expenses Strategic news and highlights Expanded internal deployments of 3rd Gen EPYC processors at multiple leading Cloud providers Significant growth in both Cloud and Enterprise, including more than 100 3rd Gen EPYC platforms available from OEMs Previewed 4th Gen EPYC processors, codenamed “Genoa”, coming later in 2022 and featuring up to 96 "Zen 4" cores with next-gen memory and I/O Announced 4th Gen EPYC processors, codenamed "Bergamo", coming in 1H 2023 and featuring up to 128 cores and power efficiency for Cloud Game console demand continues to outpace all prior generations ● ● ● ENTERPRISE, EMBEDDED AND SEMI-CUSTOM SEGMENT Q4 2021 ● ● Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 AMD#1010 5500 5000 4500 4000 3500 3000 2500 $1,786 Q1'20 $1,932 Q2'20 REVENUE TREND ($ IN MILLIONS) Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 $2,801 Q3'20 $3,244 Q4'20 $3,445 Q1'21 $3,850 Q2'21 $4,313 Q3'21 OUTSTANDING REVENUE GROWTH +49% y/y $4,826 Q4'21 AMD#1111 46% Q1'20 44% Q2'20 GROSS MARGIN TREND (GAAP AND NON-GAAP)¹ 44% Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Q3'20 45% 46% 48% Q2'21 48% Q4'20 Q1'21 STRONG GROSS MARGIN EXPANSION 1. Q3'21 +560 bps y/y 50% Q4'21 See Appendices for GAAP to Non-GAAP reconciliation AMD#12Axis Title 12 $0.14 Q1'20 EARNINGS PER SHARE TREND (GAAP) $0.13 Q2'20 $0.32 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Q3'20 1 $1.451 $1.06 Valuation Allowance Release $0.39 Q4'20 $0.45 Q1'21 $0.58 Q2'21 $0.75 Q3'21 SIGNIFICANT GROWTH IN PROFITABILITY +105% y/y¹ $0.80 Q4'21 1. In Q4 2020, AMD released $1.3 billion of its $2.9 billion income tax valuation allowance. The valuation allowance release had a $1.06 benefit to Q4 2020 earnings per share. AMD#1313 $0.18 Q1'20 EARNINGS PER SHARE TREND (NON-GAAP)¹ $0.18 Q2'20 $0.41 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Q3'20 $0.52 $0.52 $0.63 $0.73 Q4'20 Q1'21 Q2'21 SIGNIFICANT GROWTH IN PROFITABILITY Q3'21 +77% yly $0.92 Q4'21 1. See Appendices for GAAP to Non-GAAP reconciliation AMD#1414 FY 2021 SUMMARY P&L GAAP ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expenses/Revenue % Operating Income Operating Margin % Net Income 1,2 Earnings Per Share 1,2,3 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 2021 $16,434 $7,929 48% $4,293 26% $3,648 22% $3,162 $2.57 - 2020 $9,763 $4,347 45% $2,978 31% $1,369 14% $2,490 $2.06 Y/Y Up 68% Up 82% Up 370bps Up 44% Down 5pp Up 166% Up 8pp Up 27% Up 25% 1. Includes a higher tax rate beginning in Q1 2021 2. In Q4 2020, AMD released $1.3 billion of its $2.9 billion income tax valuation allowance. The valuation allowance release had a $1.07 benefit to annual earnings per share. 3. See Appendices for share count reference. AMD#1515 FY 2021 SUMMARY P&L-NON-GAAP¹ ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expenses/Revenue % Operating Income Operating Margin % Net Income Earnings Per Share¹ Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 2021 $16,434 $7,934 48% $3,877 24% $4,069 25% $3,435 $2.79 1. 2020 $9,763 $4,353 45% $2,696 28% $1,657 17% $1,575 $1.29 Y/Y Up 68% Up 82% Up 370bps Up 44% Down 4pp Up 146% Up 8pp Up 118% Up 117% Includes a higher tax rate beginning in Q1 2021. See Appendices for GAAP to Non-GAAP reconciliation and share count reference AMD#1616 Q4 2021 SUMMARY P&L - GAAP ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expense/Revenue % Operating Income Operating Margin % Net Income ¹,2 Earnings Per Share 1,2,3 Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 Q4'21 $4,826 $2,426 50% $1,223 25% $1,207 25% $974 $0.80 Q4'20 $3,244 $1,451 45% $881 27% $570 18% $1,781 $1.45 Y/Y Up 49% Up 67% Up 560bps Up 39% Down 2pp Up 112% Up 7pp Down 45% Down 45% Q3'21 $4,313 $2,086 48% $1,141 26% $948 22% $923 $0.75 Q/Q Up 12% Up 16% Up 190bps Up 7% Down 1pp Up 27% Up 3pp Up 6% Up 7% 1. Includes a higher tax rate beginning in Q1 2021 2. In Q4 2020, AMD released $1.3 billion of its $2.9 billion income tax valuation allowance. The valuation allowance release had a $1.06 benefit to Q4 2020 earnings per share. 3. See Appendices for share count reference. AMD#1717 Q4 2021 SUMMARY P&L - NON-GAAP¹ ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expense/Revenue % Operating Income Operating Margin % Net Income Earnings Per Share¹ Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 Q4'21 $4,826 $2,427 50% $1,103 23% $1,328 27% $1,122 $0.92 Q4'20 $3,244 $1.452 45% $789 24% $663 20% $636 $0.52 1. Y/Y Up 49% Up 67% Up 560bps Up 40% Down 1pp Up 100% Up 7pp Up 76% Up 77% Q3'21 $4,313 $2,087 48% $1,035 24% $1,055 24% $893 $0.73 Q/Q Up 12% Up 16% Up 190bps Up 7% Down 1pp Up 26% Up 3pp Up 26% Up 26% Includes a higher tax rate beginning in Q1 2021. See Appendices for GAAP to Non-GAAP reconciliation and share count reference AMD#1818 ($ in millions) Computing and Graphics Net Revenue Operating Income Enterprise, Embedded and Semi-Custom Net Revenue Q4 AND FY 2021 SEGMENT RESULTS Operating Income All Other Category Operating Loss TOTAL Net Revenue Operating Income Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Q4'21 $2,584 $566 $2,242 $762 $(121) $4,826 $1,207 Q4'20 $1,960 $420 $1,284 $243 $(93) $3,244 $570 Y/Y Up 32% Up 35% Up 75% Up 214% Down 30% Up 49% Up 112% Q3'21 $2,398 $513 $1,915 $542 Q/Q $4,313 $948 Up 8% Up 10% Up 17% Up 41% $(107) Down 13% Up 12% Up 27% 2021 $9,332 $2,090 $7,102 $1,979 $(421) $16,434 $3,648 2020 $6,432 $1,266 $3,331 $391 $(288) $9,763 $1,369 Y/Y Up 45% Up 65% Up 113% Up 406% Down 46% Up 68% Up 166% AMD#1919 Q4 AND FY 2021 SUMMARY BALANCE SHEET ITEMS ($ in millions) Cash, Cash Equivalents and Short-term Investments Accounts Receivable, Net Inventories Total Debt (principal amount)1 Total Debt, Net¹ Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Q4 & FY21 Q4 & FY20 $3,608 $2,706 $1,955 $313 $313 $2,290 $2,066 $1,399 $338 $330 Y/Y Up $1,318 Up $640 Up $556 Down $25 Down $17 STRONG BALANCE SHEET Q3'21 $3,608 $2,224 $1,902 $313 $313 Q/Q Flat Up $482 Up $53 Flat Flat 1. See Appendices for Total Debt reconciliation AMD#2020 1. Revenue 2. FINANCIAL OUTLOOK - NON-GAAP Q1 2022 ~$5.0 Billion +/- $100 Million ~50.5% Gross Margin % Operating Expenses Operating Expenses/Revenue % Interest Expense, Taxes and Other Effective Tax Rate Cash Tax Rate Diluted Share Count² Note: Guidance does not contemplate the addition of Xilinx as the transaction has not yet closed. See Cautionary Statement on Slide 2. These forward-looking outlook statements and non-GAAP measures are based on current expectations as of February 1, 2022, and assumptions and beliefs that involve numerous risks and uncertainties. AMD undertakes no intent or obligation to publicly update or revise its outlook statements as a result of new information, future events or otherwise, except as may be required by law. All items, except revenue, are on a non-GAAP basis. Adjustments to arrive at the GAAP financial outlook typically include stock-based compensation, non-cash interest expense related to convertible debt, income tax provision, equity income in investee, and other non-recurring items such as loss on debt redemption/conversion, impairment charges and acquisition-related costs. The timing and impact of such adjustments are dependent on future events that are typically uncertain or outside of AMD's control; therefore, a reconciliation to equivalent GAAP measures is not practicable at this time. Refer to Diluted Share Count overview in the Appendices Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 ~$1.2 Billion ~24% ~$207 Million 1 FY 2022 -$21.5 Billion Growth of ~31% y/y ~51% ~24% ~15% of pre-tax income ~9% of pre-tax income ~1.22 billion shares AMD#21Q4 2021 SUMMARY Record Revenue $4.8B Up 49% Y/Y, 12% Q/Q Gross Margin of 50% Up More Than 5 pp Y/Y Operating Income Doubled Y/Y FREE CASH FLOW OF $736 MILLION 21 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Operating Cash Flow of $822M AMD#2222 FY 2021 SUMMARY Record Annual Revenue of $16.4B, Up 68% Y/Y Gross Margin of 48% Up More Than 3 pp Y/Y Operating Cash Flow of $3.5B, Up 229% Y/Y Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Repurchased $1.8B in Common Stock RECORD GAAP & NON-GAAP PROFITABILTY & EPS AMD#2323 FORTUNE 21 COMPASS AWARD CHANGE THE 2020 WORLD INNOVATION 2020 AMD'S COMMITMENT TO ESG RBA CDP SUPPLIER ENGAGEMENT LEADER 2020 ENVIRONMENTAL Steadfast commitment to environmental stewardship and contributing to our local communities = Bloomberg Gender Equality Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Index 2022 E BEST HUMAN RIGHTS MERICA PLACES TO WORK 2022 for LGBTQ+ Equality 100% CORPORATE EQUALITY INDEX SOCIAL Creating a culture that drives innovation by fostering diversity, inclusion and belonging ME 3BL DIA 100 BEST CORPORATE CITIZENS 2021 t FTSE4Good CORPORATE RESPONSIBILITY REPORT ON AMD.COM Corporate ESG Performance RATED BY ISS ESG Prime GOVERNANCE Delivering leadership products with integrity, innovation and quality in order to help solve global challenges AMD#2424 AMD BUILDING THE BEST Leadership Roadmaps Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 Increasing Market Share Execution Excellence Outstanding Financial Performance AMD#2525 AMD XILINX. The Industry's High Performance and Adaptive Computing Leader EXPECT COMPLETION OF THE TRANSACTION IN THE FIRST QUARTER 2022 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 AMD#2626 APPENDICES Reconciliation of GAAP to Non-GAAP Gross Profit and Gross Margin (Millions) GAAP gross profit GAAP gross margin % Stock-based compensation Non-GAAP gross profit Non-GAAP gross margin % (Millions) GAAP operating expenses GAAP Operating Expenses/Revenue % Stock-based compensation Acquisition-related costs. Non-GAAP operating expenses Non-GAAP Operating Expenses/Revenue % SA Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 Reconciliation of GAAP to Non-GAAP Operating Expenses $ $ EA 2021 Q1'20 Q2'20 Q3'20 Q4'20 Q1'21 Q2'21 Q3'21 Q4'21 2020 818 $ 848 $ 1,230 $ 1,451 $ 1,587 $ 1,830 $2,086 $ 2,426 $ 4,347 $ 7,929 50% 45% 48% 46% 44% 45% 46% 48% 48% 44% 2 1 2 1 2 1 1 5 1 $1,231 $ 1,452 $ 1,588 $ 1,832 45% 6 $2,087 $ 2,427 $ 4,353 $ 7,934 820 $ 850 46% 44% 44% 46% 48% 48% 45% 50% 48% $ $ SA Q4'21 2021 2020 Q4'20 Q3'21 1,223 $ 881 $ 1,141 $ 4,293 $ 2,978 25% 27% 26% 26% 31% 111 78 98 374 268 9 14 8 42 14 789 1,035 $ 3,877 $ 2,696 24% 24% 24% 28% 1,103 $ 23% $ AMD#27APPENDICES Reconciliation of GAAP Operating Income to Non-GAAP Operating Income Q4'21 Q4'20 2021 $ 1,207 $ 570 $ 948 $ 3,648 18% 22% 25% 112 9 79 99 14 8 663 $ 1,055 $ 4,069 1,328 27% 20% 24% 25% (Millions) GAAP operating income GAAP operating margin % Stock-based compensation Acquisition-related costs Non-GAAP operating income Non-GAAP operating margin % 27 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 $ GA $ Q3'21 22% 379 42 2020 $ 1,369 14% 274 14 $1,657 17% AMD#28APPENDICES Reconciliation of GAAP to Non-GAAP Net Income / Earnings Per Share (Millions, except per share data) Q1'20 Q2'20 Q3'20 GAAP net income / earnings per share $ 162 $0.14 $ 157 $ 0.13 Loss on debt redemption/conversion (Gains) losses on equity investments, net Non-cash interest expense related to convertible debt Stock-based compensation Equity income in investee Acquisition-related costs Release of valuation allowance on deferred tax assets Income tax provision Non-GAAP net income / earnings per share Shares used and net income adjustment in earnings per share calculation Shares used in per share calculation (GAAP) (1) Interest expense add back to GAAP net income (1) Shares used in per share calculation (Non-GAAP) Interest expense add back to Non-GAAP net income 28 I Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 I - 2 59 I I T I I T 0.04 - I T I 1,224 $ 4 1,224 $ 2 I 2 60 0.05 (1) I - I (2) - - I I Q4'20 Q1'21 $390 $0.32 $ 1,781 $ 1.45 $ 555 $ 0.45 38 0.03 16 0.01 14 0.02 1,227 $ 3 1,227 $ 1 - 2 76 (1) I — I I 0.06 - (1) (4) $ 222 $ 0.18 $216 $ 0.18 $ 501 $ 0.41 - - T 1,215 $ 1 1,230 $ 1 I 79 (3) 14 T T 0.06 EA - 0.01 (1,301) (1.06) 50 0.05 $ 636 $0.52 1,226 $ 1,232 $ - T I 85 T 0.07 (2) 15 0.01 I I Q2'21 $710 $ 0.58 1 1,231 $ 1,233 $ I I I (2) 10 I 83 0.06 T 0.01 I Q3'21 1,232 $ 1,232 $ - $923 $0.75 $974 $0.80 I (60)| (0.05) 99 (2) 0.08 0.01 Q4'21 1,230 $ - 1,230 $ (4) - 9 112 0.09 I I I I (25)| (0.03) (24) (0.02) (75)| (0.06) 31 0.03 $ 642 $0.52 $ 778 $ 0.63 $ 893 $ 0.73 $ 1,122 $ 0.92 AMD I (1) Q1'20 and Q2'20 GAAP diluted EPS calculation includes 31 million shares related to the assumed conversion of the Company's 2026 Convertible Notes and the associated $4 million and $3 million interest expense, respectively, add-back to net income under the "if converted" method. Q3'20 and Q4'20 GAAP diluted EPS calculation includes 11 million and 3 million shares, respectively, related to the assumed conversion of the Company's 2026 Convertible Notes and the associated $1 million and $0 million interest expense, respectively, add-back to net income under the "if converted" method. The 20 million (15 million weighted-average), 8 million shares (6 million weighted-average) and 3 million shares (2 million weighted-average) issued in exchange for $165 million, $60 million and $24 million of convertible debt in Q3'20, Q4'20 and Q1'21, respectively, were not included as their inclusion would have been anti-dilutive. I I 1,222 $ - 1,222 $ -#29APPENDICES Reconciliation of GAAP to Non-GAAP Net Income / Earnings Per Share (Millions, except per share data) GAAP net income / earnings per share Loss on debt redemption/conversion (Gains) losses on equity investments, net Non-cash interest expense related to convertible debt Stock-based compensation Equity income in investee Acquisition-related costs Release of valuation allowance on deferred tax assets Income tax provision Non-GAAP net income / earnings per share Shares used and net income adjustment in earnings per share calculation Shares used in per share calculation (GAAP) (1) Interest expense add back to GAAP net income (1) Shares used in per share calculation (Non-GAAP) Interest expense add back to Non-GAAP net income 29 2020 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 2021 $ 2,490 $2.06 $3,162 $ 2.57 54 0.04 CO 274 (5) 14 (1,301) 43 $1,575 0.22 0.01 (1.07) 7 (56) (0.04) 379 (6) 42 1,207 $ 1 1,228 $ 4 I 0.03 (93) T 0.31 0.03 I (0.08) $1.29 $3,435 $ 2.79 1,229 $ 1,229 $ - (1) For the year ended December 26, 2020, GAAP diluted EPS calculations include 3 million shares related to the assumed conversion of the Company's 2026 Convertible Notes and the associated $1 million interest expense add-back to net income under the "if converted" method. For the year ended December 26, 2020. Non-GAAP diluted EPS calculations include 24 million shares related to the assumed conversion of the Company's 2026 Convertible Notes and the associated $4 million interest expense add-back to net income under the "if converted" method. T AMD#3030 APPENDICES Share Count Overview Shares (millions) (1) Basic Shares Dilutive impacts from: Employee Equity Grants (2) Diluted Shares (without 2026 Convertible Notes) 2026 Convertible Notes - GAAP (3) Diluted Shares (with 2026 Convertible Notes) - GAAP 2026 Convertible Notes - Non-GAAP (3) Diluted Shares (with 2026 Convertible Notes) - Non-GAAP Q1'21 Actual 1,213 18 1,231 Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 1,231 2 1,233 Q2'21 Actual 1,216 16 1,232 1,232 1,232 Q3'21 Actual 1,214 16 1,230 1,230 1,230 Q4'21 Actual 1,208 14 1,222 1,222 1,222 2021 Q1'22 2022 Actual Estimate (4) Estimate (4) 1,213 1,202 1,205 16 1,229 1,229 1,229 14 1,216 1,216 1,216 11 1,216 1,216 1,216 The table above provides actual share count for Q1'21, Q2'21, Q3'21, Q4'21and FY 2021 and an estimate of share count that may be used when calculating GAAP and non-GAAP diluted earnings per share for Q1'22 and FY 2022. (1) Share counts are weighted average shares. (2) The dilutive impact of employee equity grants is based on the Treasury Stock method and is dependent upon the average stock price during the period. The Q1'21, Q2'21 and Q3'21 average stock price was $86.88, $80.20, and $101.58, respectively. Q4'21 average stock price was $131.29. This price was assumed for Q1'22 and FY22 average stock price estimates. (3) The dilutive impact from the 2.125% Convertible Senior Notes due 2026 (2026 Convertible Notes) is based on the If-Converted method, where the interest costs associated with the 2026 Convertible Notes are added back to the Net Income and the shares underlying the 2026 Convertible Notes are assumed to be converted and are added to the share count. The impact from the 2026 Convertible Notes, if dilutive, is included in diluted EPS calculation. For the GAAP computation, the add-back to net income includes cash and non-cash interest expense, while only the cash interest expense is added back to the non-GAAP net income. The dilutive shares associated with the 2026 Convertible Notes reflect the weighted average shares subject to conversion during each period. During Q1'21, 3 million shares of the Company's common stock (2 million shares weighted) were issued to convert $24 million of the outstanding 2026 Convertible Notes. (4) Includes common stock repurchases subsequent to FY 2021 year end through February 1, 2022 AMD#31APPENDICES Reconciliation of Operating Cash Flow to Free Cash Flow Q4'21 Q4'20 31 (Millions) Operating cash flow Operating cash flow margin % Purchases of property and equipment Free cash flow Free cash flow margin % Total Debt (Net) (Millions) 7.50% Senior Notes due 2022 2.125% Convertible Senior Notes due 2026 Total Debt (principal amount) Unamortized debt discount associated with 2.125% Convertible Senior Notes due 2026 Unamortized debt issuance costs Total Debt (net) Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 $ EA GA $ $ 822 17% (86) 736 15% Q4'21 | 312 $ 1 313 $ — $ 554 $ 17% 313 $ $ (74) 480 15% Q4'20 312 26 338 (7) (1) 330 $ $ $ $ 2021 3,521 21% (301) 3,220 20% Q3'21 312 1 313 T T 313 $ $ 2020 1,071 11% (294) 777 8% AMD#3232 ENDNOTES TM R5K-002: Testing by AMD Performance labs as of 5/28/2021 based on the average FPS of 20 PC games at 1920x1080 with the High image quality preset using an AMD Ryzen ™M 9 5900X processor vs. Core i9-11900K. For Ryzen 5000 G-Series processors testing as of 5/5/2021 based on the average FPS of 11 PC games at 1920x1080 with the low image quality preset using an AMD Ryzen ™M 7 5700G vs Core i7-11700, both configured with integrated graphics. Results may vary. R5K-002.R5K-050: Testing by AMD Performance Labs as of December 11, 2020 using an AMD Ryzen 9 5900 and Intel Core i9-10900, each similarly configured and tested with an NVIDIA GeForce RTX 2080 Ti graphics card. Results may vary. R5K-002. CZM-35: Tested by AMD Labs in December 2020. The Ryzen 5000 series mobile processors are the fastest mobile processors with the highest-performing single-thread and multi-thread performance available on an x86 mobile processor, measured with Cinebench R.20 1T and Cinebench R20 nT respectively, using similarly configured systems with Ryzen 9 4900H, Ryzen 9 5980HX and Ryzen 5980HS processors vs i9-10980HK, Core i7-1185G7 processors. Performance may vary. CZM-35. 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