SEA Health Tech Investment Insights

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#1INSEAD October 9, 2020 Southeast Asia VC Health Tech Landscape INSEAD Plessis Mornay Learning Space Danny Strauss, Isaac Bang, Josiah Liang, Mokshda Wanchoo, Raoul Laitat, Zarah Liu Parvis Exerative Education Learning Space Cercie Clos St Merry Residence#2INSEAD This project assesses the SEA Health Tech landscape from a VC lens MEDICAL Rat NW What this report is: High level trend analysis ☐ Regulatory scan Macro review of the healthcare and e- Health space and trends Which vertical is expected to grow the most? What are the key growth drivers? What are the key trends in the next 12 - 18 months? List of companies by country and vertical An overview of numerous startups and VCs currently active in the region Within each vertical, what are some of the most promising startups for IFC to explore? Who are the major investors in the region? What this report is not: Detailed due diligence of startups ■ The research does not include a review of the startup valuation " No interview has been conducted with the founding members to assess their ambition and skill The startup growth strategy's soundness has not been reviewed in detail Exhaustive list of HealthTech ventures active in the region with international headquarter The research was executed primarily with a focus on ventures based in SE Asia and with operations in a select 4 SE Asian countries This report and the views presented within are solely the work of INSEAD's students for IFC's use, and do not represent IFC's views. 2#3Contents Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines INSEAD#4Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines#5Executive Summary Healthcare in SEA Challenges and Opportunities Investment Landscape Investment Recommendations • • • • • • • • • • • Healthcare Expenditure in SEA is on the rise, growing even faster than GDP. At the current pace, it is expected that by 2025, total healthcare spending could accelerate up to ~USD 740 bn from the current ~USD 425 bn. This growth is primarily driven by an ageing population (% of population above 60 will increase from 9.6% in 2016 to 21.1% in 2050, driven by the increased life expectancy of elders and reduced fertility rates of an increasingly wealthy population) and prevalence of non-communicable diseases (Smoking and Overweightness prevalent in at least 20% of the population in each of the target regions). The key challenges in SEA Healthcare are caused by capacity shortages and fiscal constraints, which are further compounded by country specific issues such as geographic dispersion. Despite the increasing demand, government health expenditure as % of GDP has stayed stagnant over the years. Rising income groups and an affluent population have fueled the demand for higher quality of care Health Tech is well positioned to solve these challenges as Technology can play a key role in delivering convenient, cost-effective, and high-quality treatment. Further, digital penetration is rising rapidly, supported by significant push from government to adopt technology. The Health Tech sector in SEA saw record breaking funding levels in 2019 as deal volume rose at a 63% CAGR 2 of the 5 largest SEA Health Tech deals in 2019 are based in Indonesia (Halodoc and Alodokter), while the others are based in Singapore Sequoia Capital, Monk's Hill Ventures, SG Innovate, Wavemaker, East Ventures are some of the funds who invested actively in SEA Health Tech in the last few years Corporates and Health Tech ventures are increasingly entering into partnerships to scale digital health Taking into account IFC's development goals, potentially investable start-ups identified through our research are: Halo Doc, Alodokter (Indonesia), Lifetrack Medical Systems, mClinica (Philippines), Medical Departures, Meticuly (Thailand), JioHealth, MyDoc, DoctorAnywhere (Vietnam) Further, potentially investable VCs that have been active in HealthTech are: East Ventures (Singapore, Indonesia, Tokyo), Intudo Ventures (Indonesia), Monk's Hill Ventures (Singapore, Indonesia, Vietnam), Wavemaker (Singapore, USA), Open Space Ventures (Singapore) INSEAD 5#6Key Findings INSEAD Indonesia Vietnam Thailand Philippines • • • • • • • • • • Between 2014 and 2019, Indonesia deployed its universal health coverage called Jaminan Kesehatan Nasional (JKN), thanks to which citizens are entitled to free healthcare or healthcare at very low cost. The private sector represents 60% of healthcare overlays. While widely available in first-tier cities; private hospital group see second-tier cities as promising opportunities for expansion. There is a significant imbalance of supply and demand at the moment. In Indonesia, there is still no general law on data protection. Patient rights however are guaranteed by several laws. Vietnam's healthcare system functions as a mixture of public and private provision, with a dominant public side. 87% of citizens hold social health insurance and the government continues to finance hospital construction. In addition, private healthcare popularity is increasing and holds importance for 60%+ of outpatient services Lack of access to care, especially in rural areas, remains a major challenge, as do equipment and capacity shortages. Government incentives exist for investment in healthcare and tech. Health Tech will support digitalization of public and private healthcare and will help with the evolution of relatively new data and tech regulation. Thailand's universal healthcare system (highly centralized) is expensive and will need changes in order to support its aging population, whether through decentralization of healthcare systems and/or tech innovations There's a looming shortage of healthcare professionals, and a rural-urban gap in terms of accessibility to high quality healthcare, providing an opportunity for technology to address some of these issues The government is set on a goal to make Thailand the "#1 Medical Hub of Asia" by pushing for support of its medical tourism industry, and providing incentives for R&D in technology and innovation Access to healthcare remains highly inequal across the Philippines, particularly in areas like Mindanao, despite gov't efforts to ensure universal healthcare. A key challenge is the high levels of fragmentation across both public and private health sectors, which has led to inefficiencies and high costs. Limitations in national social health insurance have also contributed to high out-of-pocket healthcare expenditure, particularly on medicines. The gov't is supportive of digital health efforts, but implementation is likely to remain challenging.#7Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines#8Market Overview - Healthcare in Southeast Asia INSEAD#9HealthCare Expenditure is on the rise, growing even faster than GDP Growth of Health Expenditure Per Capita vs. GDP Per Capita (Index chart base year: 2012 = 100) 160 140 Indonesia 160 Vietnam 160 Thailand 140 140 120 120 120 100 100 100 80 80 80 2012 2013 2014 2015 2016 2017 2012 2013 2014 2015 2016 2017 2012 2013 2014 2015 2016 2017 160 Philippines 160 Malaysia 160 Singapore 140 140 140 120 120 120 100 100 100 80 80 80 2012 2013 2014 2015 2016 2017 2012 2013 2014 2015 2016 2017 Total Health Expenditure per Capita 2012 2013 2014 2015 2016 2017 GDP Per Capita With healthcare cost outpacing economic growth in nearly all ASEAN nations, it is expected that by 2025, total healthcare spending could accelerate up to ~USD 740 billion from the current ~USD 425 billion. Sources: World Health Organization, BMI Report, Solidiance Analysis ("The ~USD 320 Billion Healthcare Challenge in ASEAN") INSEAD 9#10INSEAD The growth is primarily driven by an ageing population and prevalence of non-communicable diseases 1 Ageing Population Age CAGR 2015 - 2040 (%) 2 Prevalence of Non-Communicable Diseases Prevalence Of Smoking (2015), Overweight (2016), And Obesity (2016), (%) 00-14 15-64 1.4% 0.8% 0.4% 0.4% -0.4% -0.3% -0.2% 0.0% -0.7% -1.2% 65 and above 4.4% 4.0% 3.6% 3.7% 2.0% Smoking 39.9% Overweight 31.6% 25.7% 23.6% 24.4% 21.2% 22.3% 20.4% Obesity 9.2% 5.7% 3.5% 4.7% ■Indonesia ■ Vietnam ■Thailand ■Philippines OECD Nearly all 6 ASEAN nations show either negative or close-to-zero growth for the youngest part of their population (age years 0-14). While the workforce age part of the population (age years 15-64) in most nations is still slowly growing, the retirement age population (age group 65-above) is outpacing them rapidly, with relative growth rates 3- 10 times higher than the working age population. In SEA, 9.6% of the total population was 60 and above in 2016 but is expected to more than double to 21.1% by 2050, driven by the increased life expectancy of elders and reduced fertility rates of an increasingly wealthy population. ■Indonesia ■ Vietnam ■Thailand ■Philippines Overweight and obesity (metabolic risk indicators) as well as smoking (typical risk behaviors) are highly prevalent in SEA and continue to increase. This will translate into a high prevalence of severe non-communicable diseases in the future. This trend will compound the effects of the increased population age in the ASEAN 6 nations. Sources: World Health Organization, United Nations, OECD, Ministry of Health of respective countries, Solidiance Analysis ("The ~USD 320 Billion Healthcare Challenge in ASEAN") 10#11Market Comparison Indonesia Vietnam Thailand Philippines India China Estimated total healthcare US$40 billion expenditure Healthcare expenditure per capita (2017) (~3% of GDP; ~10-11% CAGR 2016-2020) US$115 (1.44% CAGR 2012-2017) US$19 billion (~5.5% of GDP; ~10% CAGR 2016-2020) US$25 billion (~3.75% of GDP; ~3% CAGR 2016-2020) US$130 (3.68% CAGR 2012-2017) US$247 (3.66% CAGR 2012-2017) US$17 billion (~4.45% of GDP; ~10-11% CAGR 2016-2020) US$133 (3.31% CAGR 2012-2017) US$100 billion (~3.5% of GDP) US$69 (7.15% CAGR 2012-2017) US$700 billion (~5.15% of GDP) US$441 (9.23% CAGR 2012-2017) 240 240 240 240 220 180 440 220 220 220 200 160 420 400 200 200 200 180 140 380 180 180 180 160 120 360 140 160 160 160 100 340 140 140 140 80 120 320 120 120 120 60 100 300 2012 2013 2014 2015 2016 2017 100 100 100 40 280 2012 2013 2014 2015 2016 201: 2012 2013 2014 2015 2016 2017 2012 2013 2014 2015 2016 2017 2012 2013 2014 2015 2016 2017 2012 2013 2014 2015 2016 2017 Ease of doing business ranking 73rd (out of 190 countries) Digital competitiveness ranking 73rd (out of 141 countries) 70th 70th 21st 55th 95th 63rd 31st 81st 101st 54th Source: Economist Intelligence Unit report on SEA Healthcare Market; World Bank; Cisco Digital Competitiveness Index 11#12Market Overview - Challenges and Opportunities INSEAD#13The key challenges in SEA Healthcare are caused by capacity shortages and fiscal constraints (1/2) 1 Hospital Beds (per 1000 population) Capacity Constraints INSEAD 3.7 2.6 2.4 2.1 1.9 1.2 1.0 Indonesia Vietnam Thailand Philippines Malaysia Singapore OECD Physicians (per 1000 population) 2.6 2.0 1.3 1.5 0.8 0.3 0.5 Indonesia Vietnam Thailand Philippines Malaysia Singapore OECD Nurses (per 1000 population) . . 8.4 . 6.0 3.4 2.4 1.3 1.4 0.2 Indonesia Vietnam Thailand Philippines Malaysia Singapore OECD SEA is severely lagging in terms of medical infrastructure and healthcare professionals. Shortage of hospital beds and qualified physicians and nurses results in bed occupancy rates of over 100%, well above WHO's recommendation of 80% Further, patients face prolonged wait times and very short consultation time with their doctors. SEA is not equipped to meet the current demand of healthcare. Sources: World Bank, World Health Organization. Note: Data pertains to the latest year available; in most cases this is between 2014-15. 13#14The key challenges in SEA Healthcare are caused by capacity shortages and fiscal constraints (2/2) 2 INSEAD Fiscal Constraints Government Health Expenditure per Capita, US$ PPP Government Health Expenditure as % of Total Health Expenditure 821.5 76.1% 510.7 178.0 182.7 118.6 Indonesia Vietnam Thailand Philippines World 48.4% 48.6% Indonesia Vietnam 59.5% 31.9% Thailand Philippines World Government health expenditure per capita, PPP is substantially below the world average Government health expenditure as % of total health expenditure is more than 10% below the world average in each country, other than Thailand. Government Health Expenditure as % of GDP ■2013 ■ 2014 ■2015 ■ 2016 3.0% 2017 2.4% 2.4% 2.7% 2.7% 2.6% 2.8% 2.7% 2.9% 2.9% 0.9% 1.1% 1.2% 1.4% 1.4% 1.2% 1.1% 1.4% 1.4% 1.4% Indonesia Vietnam Thailand Philippines 5.7% 5.8% 5.9% 6.0% 5.9% World Government health expenditure as % of GDP has stagnated over the years, suggesting an inability to spend more. Overall, governments are unlikely to have sufficient means to meet the increased demand for healthcare with equal increases of healthcare spending. Source: World Bank. Note: Unless otherwise stated, data pertains to the latest year available; in most cases this is 2017. 14#15Rising income groups and an affluent population have fueled the demand for higher quality of care INSEAD Existing healthcare systems are subpar in terms of quality Patients often do not have enough time with their doctor; The typical experience is three minutes of care after a three-hour wait Public Healthcare Centers often do not provide all the services they are supposed to Lack of sufficient equipment for surgery and intensive care units in public hospitals Significant variation in quality of medical equipment between national and provincial hospitals + There is a marked rise in the size of the affluent and middle-class across SEA In 2017, the middle class and affluent customers made up -60% population in Thailand and ~44% in Indonesia 50 million new consumers will join the ranks of the middle class in Indonesia, the Philippines, Thailand, Vietnam and Malaysia by 2022, contributing to the region's $300 billion middle-class disposable income There is growing demand for access to better healthcare facilities and higher quality of healthcare Sources: Monk's Hill ("How will tech meet evolving healthcare need in Southeast Asia"), Bain & Company ("Understanding Southeast Asia's Emerging Middle Class”), Consultancy Asia ("BCG report highlights the growing upper wealth classes of ASEAN") 15#16Health Tech is well positioned to solve these challenges. Technology can play a key role in delivering convenient, cost-effective, and high-quality treatment • • Convenience & Access: Technology and data can deliver the same convenience and cost savings found in other parts of the online economy, such as e-commerce. With telehealth, people in rural and other remote areas are now be able to receive an online diagnosis and access digital resources to address their needs. Cost Effective: Instead of visiting a clinic, a patient can talk to their doctor via a smartphone app, thus saving cost of travel and a day of paid work, which many travelling from remote areas must forego. High Quality: Technology can give access to higher and more standardized quality of healthcare. People often travelled for hours instead of visiting their local doctors because of the inadequacy of professional level and medical equipment available locally. • • • SEA's Readiness for Health Tech 69% 67% 48% 43% % Digital Penetration Indonesia Vietnam Thailand Philippines Rapidly Increasing # of Internet Users in SEA 260M 360M 2015 2019 Digital Penetration: Just over a decade ago, four in five Southeast Asians had limited to no Internet connectivity. Today, there are 360+ million Internet users in the region, with 100M users added in the last 4 years. Receptiveness of Healthcare Professionals: According to a PwC Health Research Institute survey, 85% of clinicians in Southeast Asia said they would use data from apps, wearables and some form of technology in future treatments Signs of governmental push to adopt technology: Both the Philippines and Thailand gov'ts, for example, have introduced measures to incorporate technology into their healthcare system Sources: Monk's Hill ("How will tech meet evolving healthcare need in Southeast Asia"), Google & Temasek / Bain, e-Conomy SEA 2019 ("Southeast Asia's $100 billion Internet economy"), World Bank INSEAD 16#17Market Overview - Investment Landscape INSEAD#18Overview of SEA Health Tech Investment Landscape SEA Health Tech Funding (US$mn) Singapore and Indonesia continue to account for majority of the region's funding... 100% 80% #of Deals 30 39 51 53 47 60% 40% 266 20% 0% CAGR 63% 2016 ■Singapore ■Indonesia 118 91 54 38 2015 2016 2017 2018 2019 The Health Tech sector in SEA saw record breaking funding levels in 2019 as deal volume rose at a CAGR of 63% even as number of deals fell by 6 2017 Thailand ■Malaysia 2018 ■Vietnam INSEAD 2019 Phillippines ■Myanmar ...With a roughly even distribution of funding across sub-verticals (1) Early & Series A volumes signal a healthy pipeline for innovation (1) Online Health Communities, Other, 10% 4% Online Marketplace, 7% Telemedicine, 7% Remote Monitoring, 8% Medical Diagnostics, 8% Medical Education, 9% Source: Galen Growth Asia Health Tech Investment Landscape Report 2019; Note (1) Data pertains to year 2019. Health Management Solutions, 14% Series D& Beyond 3% Series C 5% Wellness, 13% Series B 14% Series A 26% Health Services Search, 12% Patient Solutions, 9% Early 53% 18#192 of the 5 largest SEA Health Tech deals in 2019 are based in our target region US$65mn halodoc Sector: Health Management Solutions Description: Health-tech platform that connects patients with doctors, insurance, labs, and pharmacies in one simple mobile application Location: Indonesia Stage: Series B # of Investors: 4 Key Investors: UOB Venture Management, Singtel Innov8, Korea Investment Partners, WuXi AppTec, Prudential Financial, Bill & Melinda Gates Foundation, Allianz X US$35mn ❤biofourmis Sector: Patient Solutions Description: Patient Solution systems that augment Personalized Care and Therapies using Digital Therapeutics Location: Singapore Stage: Series B # of Investors: 7 Key Investors: Sequoia Capital India, MassMutual Ventures, Singapore Economic Development Board, Jianke, Openspace Ventures(E), Aviva Ventures(E), SGInnovate(E) US$33mn ALODOKTER Sector: TeleHealth, InsurTech Description: Health portal that provides high quality content and interaction with qualified Indonesian doctors Location: Indonesia Stage: Series C # of Investors: 7 Key Investors: Sequis Life, Softbank (E), Golden Gate (E), Philips, Heritas Capital, Hera Capital, Dayli Partners US$25mn US$20mn Xcxagroup Sector: Health Management Solutions Description: Al-powered platform that provides personalized health & wellness offerings based on the individual's health data. Location: Singapore Stage: Series C # of Investors: 12 Key Investors: HSBC, Singtel Innov8, Telkom Indonesia MDI Ventures, Sumitomo Corporation Equity Asia, Muang Thai Fuchsia Ventures, Humanica, Heritas Venture Fund Source: Crunchbase, Galen Growth Asia Health Tech Investment Landscape Report 2019 LUCENCE DIAGNOSTICS Sector: Medical Diagnostics Description: Diagnostics Technology Platform that develops advanced liquid biopsy blood tests that guiding cancer care by molecular profiling Location: Singapore Stage: Series A # of Investors: 5 Key Investors: IHH Healthcare Berhad, SGInnovate, Heliconia Capital (subsidiary of Temasek), Lim Kaling, Boon Hwee Koh Lead Investors INSEAD 19#20Some of the active investors in SEA Health Tech include... VER ERITAS Office: Singapore SGINNOVATE Office: Singapore biofourmis b LUCENCE DIAGNOSTICS SEQUOIA ALODOKTER Xcxagroup Office: India +biofourmis zenyum MONK'S HILL VENTURES Office: Singapore Jio Health botmd openspace VENTURES Office: Singapore Chalodoc biofourmis Singtel innov8 Office: Singapore U halodoc Xcxagroup wavemaker -PARTNERS- Office: Singapore >Healint mydoc) Simplify Healthcare Cast Ventures Office: Indonesia MEDICO * konsula Notable ventures funded by the investors INSEAD 20#21Digital health platforms and telehealth were the sub-verticals with most venture activity Number of Ventures by Sub-vertical & Country Digital health platforms 5 1 6 4 Telehealth and remote care 3 4 2 4 Healthcare supply chain and/or operational digitization 2 1 1 1 Biotechnology 2 Device and automation tech 1 1 Electronic health records 1 0 5 10 15 Indonesia ■Vietnam Thailand Philippines 20 20 • Most ventures were found in sub-verticals focused on making basic healthcare more accessible and cost- effective - the major challenge across the SEA countries analyzed. We saw significantly fewer ventures in spaces where tech sophistication would be the fundamental differentiator (e.g. AR/VR, Al or biotech), although there were some in Thailand (the most developed healthcare market of the four). The telehealth subvertical in particular tended to be crowded with ventures with relatively similar technology, products and business models. In B2B space, there is a large potential opportunity for ventures offering healthcare digitization/electronic health record management capabilities, given rudimentary levels of digitization in most health organizations (particularly in the public sector). However, it's unclear where local ventures' competitive advantage over established foreign players lies in this space. INSEAD 21#22A key differentiator in ventures' ability to scale is likely to be the quality of their partnerships Government Entities In Singapore, Ring MD entered into a regulatory sandbox with the Health Ministry to better integrate telemedicine into the healthcare ecosystem MINISTRY OF HEALTH SINGAPORE ringmd Insurance Providers MyDoc's telemedicine services are integrated into Prudential's customer app for PRUDENTIAL holistic health management Halodoc's teleconsultation services have been made available free-of-charge to AXA customers AXA ASIA PACIFIC halodoc ❤ Jio Healthtech Ventures DA DOCTOR ANYWHERE mydoc) Simplify Healthcare 8 平安好医生 (Ping An Good Doctor) INSEAD Established Healthcare Providers FV HOSPITAL World Class Healthcare in Vietnam In Vietnam, JioHealth established referral partnerships with certain hospitals to ensure smooth transition of patient care Other Corporate Partners gojek Doctor Anywhere partnered GoJek to provide its driver- partners convenient access to medical consultation services Grab Grab and Ping An Good Doctor entered a JV to provide access to online medical consultations & medicine delivery in SEA 22#23Market Overview - Investment Recommendations INSEAD#24Top Potential Health Tech Company Targets Based on assessment criteria from IFC and data collected on more than 35 Health Tech startups in Southeast Asia, the following companies stood out for potential investments opportunities. Expert interviews highlighted that few players will likely "take it all" and that Health Tech players will end up joining large healthcare players or large tech companies. Rising international players should be monitored regularly. Founding Year Primary Country of Operation Last Funding Round Vertical Company U halodoc 2016 Indonesia - Series B $65mn in 2019 ALODOKTER 2014 Indonesia Series C $33mn in 2019 Lifetrack Medical Systems 2012 Philippines Series A $5.7mn in 2019 ::mClinica 2012 pharmacy solutions Philippines Series A $6.3mn in 2017 MEDICAL DEPARTURES 2014 Thailand Series A $2.5mn in 2016 2017 Thailand - Series A $2.7mn in 2019 METICULY * Jio Health 2014 Vietnam Series A $5mn in 2019 mydoc) 2012 Vietnam Series A $5.2mn in 2017 Simplify Healthcare DA DOCTOR ANYWHERE 2015 Note: Further details available in the attached Excel File. Telehealth Digital health Telehealth Supply chain digitalization Digital health medical tourism Device and automation tech - 3D printed prosthetics Telehealth Telehealth Vietnam Series B $27mn in 2020 Telehealth INSEAD 24#25Future Targets to Watch Out For INSEAD We've identified the following companies as interesting and a candidate for future investments, but are too early for IFC's investing criteria: Company Founded HQ Latest Funding Health at Home 2015 Thailand bm 2018 Vietnam Seed Round Undisclosed Seed Round April 2020 newman's 2020 Indonesia Seed Round March 2020 2016 Indonesia Seed Round January 2017 TeleCTG Description Health at Home tailors and connects the right caregivers to patients with various ailments and conditions. In addition, Health at Home provides digital consultations and care management. BuyMed offers a platform to centralize the pharmaceutical distribution network in Vietnam, matching supply and demand of pharmaceuticals and commercial health items. Newman's is a Y-Combinator backed digital health clinic for men focusing on hair loss, sexual health, and smoking addiction. The platform provides access to doctor consultations and prescriptions. TeleCTG develops cardiotocography device that detects fetal heartbeat in the womb. The device is affordable enough to be purchased by rural medical workers, so abnormalities can be detected more quickly and prevent mortality of mothers and babies. Reason Thailand and other SEA countries having an aging population with low/no growth of the younger population. This startup's services will be in demand as the aging population requires more in-home care. BuyMed is backed by Sequoia Capital India's Surge early- stage accelerator, and has reported large growth in its annual revenue in the past year. It already has an immense number of verified suppliers, distributors, manufacturers, and healthcare providers on its platform. We see a huge potential for growth with new product lines and further expansion into various SEA markets. This digital health startup is tackling a niche market in Indonesia that is stigmatized in the region, allowing men to address some of these issues without having to be embarrassed to seek treatment. We see high growth potential in this niche segment of men's health. Super interesting medical device startup tackling infant and mother mortality with an affordable cardiotocography device. This especially helps rural hospitals with lower accessibility. It's in Phase I clinical trials, and we see a promising future if the it can complete all clinical trials and establish partnerships with governments and hospitals. Note: Further details available in the attached Excel File. 25#26Top Potential Health Tech VC Targets A review of the Health Tech space highlighted that Health Tech remains a niche market on which no individual player* is fully dedicated. Few companies stood out however for their narrower focus on the Southeast Asian investment space and may be suitable candidates for investment after adequate alignment on investment terms Company له. Intudo Ventures Founding Year HQ Country Indonesia, Singapore, 2009 Tokyo 2017 Indonesia 2014 MONK'S HILL VENTURES Singapore, Vietnam and Indonesia (Jakarta) 2003 Singapore, USA wavemaker openspace 2014 VENTURES Singapore Active Funds Fund VIII - $88M - June 26, 2020 Fund VI- $75M - Aug 21, 2019 Fund V - $27.5M - Jan 11, 2017 Fund III - Unknown – Mar 11, 2014 Fund II $50M - Feb 14, 2019 Fund - $20M - Feb 8, 2018 Fund II - $100M - Aug 2, 2018 Fund $80M - April 7, 2016 Fund III $111M - 2019 Fund II- $66M - 2017 Fund $6.6M - 2012 - Fund III - $90M - July 8, 2020 Fund II – $135M - Aug 14, 2018 Fund - $90M - Nov 18, 2015 Description One of the longest-serving seed investors in Southeast Asia with investment in over 160 startups with more than USD $4 billion in follow- on rounds Intudo Ventures' portfolio concentrated capitalizing on the rapid growth of private consumption and rising middle class in Indonesia Venture capital firm investing in early stage technology start up in SEA. They have offices in Singapore, Indonesia (Jakarta), and Vietnam. Early-stage VC that focuses on enterprise and deep tech companies. Openspace Ventures makes investments in early-stage technology companies based in Southeast Asia. * With the exception of CVC funds excluded from this analysis but available for review in the excel appendix Note: Further details available in the attached Excel File. INSEAD 26#27Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines#28Indonesia - Key Indicators [Indicators are for year 2019 unless otherwise stated] Economic Indicators GDP (PPP current int'l $): 3,329 bn GDP growth rate: 5.0% GDP/capita (PPP current int'l $): 11,812 GDP/capita (current US$): 4,135 Unemployment (ILO estimate): 4.7% Population below poverty line (2016): 10.9% Ease of Doing Business ranking: 73rd (out of 190) Procedures to register a business: 11 Cost of business start-up procedures (% of GNI per capita): 5.7% Mobile subscriptions / 100 inhabitants: 127 Internet users as % of population: 48% Fixed broadband subscriptions / 100 inhabitants: 3.48 Demographic Indicators Population (2020 est.): 267.03m Population growth rate (2020 est.): 0.8% Languages: Bahasa Indonesia (official), English not widely spoken. More than 700. languages are used in Indonesia. Urban population: 151.51m (56% of total) Indonesia age breakdown (2019) Percentage 30% 26.22% 24.54% 25% 22.46% 20% 15% 10% 5% 17.07% 7.78% 1.94% 0% 0-14 15-29 30-44 45-59 60-74 75+ Age (range) Healthcare Indicators INSEAD Healthcare expenditure as % of GDP (2017): 3% Healthcare expenditure per capita (2017, current US$): 114.7 USD Human Development Index ranking: 111th (out of 189) Life expectancy at birth: 73.7 years Infant mortality rate: 20.4 deaths/1,000 live births Physician density: 0.38 physicians/1,000 population Hospital bed density: 1 beds/1,000 population Private sector share of hospital beds (2013): 18% Major causes of death: 1) Stroke, 2) Heart disease, 3) Diabetes, 4) Tuberculosis, 5) Cirrhosis Sources: CIA Factbook, World Bank 28#29Indonesia's healthcare adopts a hybrid model of public and private providers and universal health coverage Overview Public Healthcare System Decentralized, in deficit, underequipped In 1999, a reform decentralized health services to provincial and district governments which are under the Ministry of Home Affairs. Between 2014 and 2019, Indonesia deployed its universal health coverage called Jaminan Kesehatan Nasional (JKN), thanks to which citizens are entitled to free healthcare or healthcare at very low cost, allowing many patients to find treatment Healthcare system suffers from structural problems, such as underfinancing, lagging numbers of hospital facilities and inequity of care especially in remote areas Authorities • Ministry of Health supervises government hospitals, provisional/ district health offices Decentralized approach: district governments take major role in managing health support and funding Financing JKN funded by certain percentage of salary contribution of employers and employees. The current program had a deficit of IRD 32 trillion in 2019 Private Healthcare Options Underequipped, lacking financial support Private providers include networks of hospitals and clinics that are managed by not-for-profit, charitable, or for-profit providers, as well as individual doctors and midwives who have dual practices. INSEAD The private sector represents 60% of healthcare overlays. 1,787 or the 2,813 hospitals are privately managed Widely available in first-tier cities; private hospital group see second-tier cities as promising opportunities for expansion Indonesia healthcare sector is at an early stage of its life cycle, with a significant imbalance of supply and demand. In 2018, the World Bank wrote that "Indonesians could be healthier with stronger public-private partnerships" Healthtech overview Favorable conditions for the rise of Digital Health MOH is working to achieve an integrated health information system. Main challenge is to integrate information from the private sector. Since 2014, the country is served by the Health Technology Assessment committee that analyses health technologies, All investments is supervised by the Indonesian Investment Coordinating. Investment can be through a legal entity or a commercial entity. Hospital investments are available to foreign investors, but the investment plan requires formal approval from the MoH. The geographical condition, combined with insufficient number and distribution of health workforce, lack of investment in facilities and difficulties in transportation is favorable for the rise of e.g. telemedicine. The MoH has included telemedicine in their 2015-2019 Strategic Plan Sources: 2016.export.gov (Healthcarere Source Guide), Oxfordbusinessgroup (Universal Coverage Public and Private Initiatives are Supporting Sector Growth) 29#30Key Challenges in the Current Healthcare System include... High rate of illegal sales of prescription drugs Lowest rate of hospital beds per inhabitants in ASEAN countries Largest archipelago with more than 17,000 islands There are 5,000 estimated unlicensed drugstores, 90,000 informal outlets Monitoring and enforcement is the responsibility of the local government Indonesia offer 310,710 hospital beds, i.e. 1.17 beds per 1000 population. This rate is the lowest among ASEAN countries and is among the lowest in the world. The country also lacks appropriate physicians (1.3/10,000 inh.), nurses and midwives (8.3/10,000 inh.) coverage. The country needs 15x its current number of doctors to reach the level of OECD countries. This complex geographical structure is a challenge to offer consistent health services across the countries and a driver for telehealth growth Rising costs of healthcare for the gov. The nominal health spending has been steadily increasing in the last 8 years, by 222% overall (reported in 2017) be remains the lower of the SEA in terms of % of GDP Digital technologies can help Indonesia overcome their current issues Sources: WHO (The Republic of Indonesia - Health System Review), 2016.export.gov (Healthcarere Source Guide), Oliver Wyman (The future of the Indonesian healthcare system) INSEAD 30#31Digital Health Indonesia's market and regulatory landscape is favorable to digital health-tech Patient rights are guaranteed by several laws, including the right to confidentiality, to information about treatment and costs, to give consent to any procedures and not to be treated negligently (see Law no. 36 of 2009 from the Ministry of Communication and Informatics). Pharmaceuticals The National Agency for Food and Drug Control supervises food and drug in Indonesia. A large volume of drugs are produced locally and need to meet the requirements of Good Manufacturing Practice (GMP) 95% of the basic ingredients are imported MoH primarily uses generics to supply the public sector (60%) Medical Equipment . Indonesia imports 97% of medical devices. . Regulations details: https://www.who.int/medical_devices/countries/r egulations/idn.pdf?ua=1 SEA research in Medical Equipment / MedTech is dominated by Singapore who invests . The pharmaceutical and medical equipment advancements are currently dominated by Singapore in SEA thanks to favorable infrastructure, stable legal environment and large investments offered by the authorities (see the 2019 budget with S$1 billion worth of measures to help businesses build 'deep' capabilities Sources: WHO (The Republic of Indonesia - Health System Review), World Bank, DLA Piper, Expert interviews . In April 2020, Reuters wrote that "Indonesia leans on Health Tech startups to cope with virus surge" INSEAD Experts highlighted that the digital health space is where most of the local new ventures will come from, with already the emergence of local 'winners' such as Halodoc and Alodokter. The Indonesian Healthtech Association offers a comprehensive list of stakeholders: https://healthtech.id/members/ Introduction of measures to support SMEs, e.g. "Let SMEs Sell Online" in 2018, with a goal of 8m SMEs selling their products via the internet by 2020. In Indonesia, there is still no general law on data protection 31#32Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines#33Vietnam - Key Indicators [Indicators are for year 2019 unless otherwise stated] Economic Indicators GDP (PPP current int'l $): 807.8 bn GDP growth rate: 7.0% GDP/capita (PPP current int'l $): 8,041 GDP/capita (current US$): 2,715 Unemployment (ILO estimate): 2.0% Population below poverty line (2017): 8% Ease of Doing Business ranking: 70th (out of 190) Procedures to register a business: 8 Cost of business start-up procedures (% of GNI per capita): 5.6% Mobile subscriptions / 100 inhabitants: 141 Internet users as % of population: 69% Fixed broadband subscriptions / 100 inhabitants: 15.35 Demographic Indicators Population (2020 est.): 96.42m Population growth rate (2020 est.): 1.0% Languages: Vietnamese (official), English (increasingly favoured as 2nd language) Urban population: 35.33m (37% of total) Vietnam age breakdown (2019) Percentage 30% 25% 23.21% 23.76% 23.18% 20% 15% 10% 5% 17.99% 8.76% 3.10% 0% 0-14 15-29 30-44 45-59 60-74 75+ Age (range) Healthcare Indicators INSEAD Healthcare expenditure as % of GDP (2017): 5.5% Healthcare expenditure per capita (2017, current US$): 129.58 USD Human Development Index ranking: 118th (out of 189) Life expectancy at birth: 74.4 years Infant mortality rate: 15.7 deaths/1,000 live births Physician density: 0.83 physicians/1,000 population Hospital bed density: 2.6 beds/1,000 population Private sector share of hospital beds (2016): 5.5% Major causes of death: 1) Stroke, 2) Heart disease, 3) Lung cancer, 4) COPD (lung disease), 5) Alzheimer's disease Sources: CIA Factbook, World Bank 33#34INSEAD Vietnam's healthcare system functions as a mixture of public and private provision, with a dominant public side • • . • Public Healthcare System Efforts by the gov't towards universal healthcare coverage 87% of the population is covered by social health insurance (1) The Government continues to finance new hospital construction to increase healthcare access for rural and urban communities (2) Vietnam's public sector has a decentralized hospital system organized into four groups(3): Private Healthcare Options • The Vietnamese private healthcare sector is relatively young, but holds an important position in outpatient care • • As of 2016, private sector only accounted for 17% of hospitals (5.5% of hospital beds), yet private hospitals provided 60%+ of outpatient services Private hospitals continue to grow, primarily in major cities and for the middle and upper class(2) National Level: Ministry of Health 46 Hospitals Provincial Level: Provincial Departments of Health 411 Hospitals + 47 Health Clinics District Level: District Offices of Health 629 Hospitals + 544 Health Clinics Communal Level: 11k Communal Health Centres Number of Hospitals in Vietnam 133 150 167 186 207 231 1,040 1,042 1,069 1,063 1,071 1,091 2011 2012 2013 ■Public Hospitals 2014 ■Private Hospitals 2015 2016 Sources: (1) World Health Organization (WHO); (2) Vietnam Briefing, 2020; (3) BDGVietnam, 2017 34#35Opportunities in both public and private healthcare, and to INSEAD leverage Government investment incentives Vietnamese government incentivizes healthcare and tech investments, provides preferential tax treatment Government Outlook: rising healthcare costs and limited public budget has the government looking to private and international investments for increasing healthcare quality and access. Further, they have set national goals in Resolution 20-NQ/TW in 5 key priority areas; public health, healthcare network, healthcare access, pharma and medical equipment innovation, and human resources Incentives: effective on January 1st, 2021, the amended Law on Investment (LOI) incentivizes investment in both healthcare and IT-related industries through preferential income tax, real estate, and credit laws. Smart health-tech investments will target national healthcare system and can benefit from free trade agreements Universal Health Coverage (UHC): today, 87.7& of Vietnam's population benefits from state-provided healthcare. However, issues arise when trying to balance supply of hospitals and physicians with demand. Pharma & Medical Devices: Vietnam has been actively negotiating various trade agreements. The EU – Vietnamese Free Trade Agreement (EVFTA), ratified in February 2020, will make it easier and cheaper for European manufacturers to sell into the Vietnamese market. Foreign pharmaceuticals make up 55% of current consumption in Vietnam. COVID: the recent pandemic has enabled Vietnam to stand as a strong example of healthcare response. From public infrastructure investment, early regulatory responses, the release of a nation-wide contract tracing app, and more. Sources: Vietnam Times, 2020; Deloitte, 2019; Our World in Data 35#36Tech startups will have a seat at the table to help Vietnam government evolve recent tech and data regulations Opportunistic health-tech in Vietnam will further the digitalization of healthcare, and work with the government to evolve and define the regulatory landscape Digitalization: in general, health-tech is a highly regulated landscape but with many uncertainties. Private hospitals with greater flexibility have been quick to adopt newer technologies, public healthcare organizations lack the resources and expertise to compete. Telemedicine: the Ministry of Health's Circular 47/2017 enables and provides guidelines for doctors to provide telemedicine services, requiring IT infrastructure and licensing standards. In April 2020, the country launched a telemedicine app designed for Covid-19 and general healthcare. 2019 saw various laws protecting user data in Vietnam, companies operating in the country to be held to regulations similar to those of GDPR Personal Data Protection: in December of 2019, the Ministry of Public Security published the first draft of the Decree on Personal Data Protection. It outlines, for the first time, legal terms to protect personal data in Vietnam. Such data includes healthcare status, genetic information, and biometric data. The decree's laws are similar to that of GDPR. Law of Cybersecurity: in January of 2019, the law was passed to promote cybersecurity. The most prominent aspect of the law is a requirement for Vietnamese and foreign enterprises to establish a representative office in Vietnam to be held responsible for the security of user data. INSEAD Sources: AusTrade, 2019; Baker McKenzie, 2020 36#37Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines#38Thailand - Key Indicators [Indicators are for year 2019 unless otherwise stated] Economic Indicators GDP (PPP current int'l $): 1,339 bn GDP growth rate: 2.4% GDP per capita (PPP current int'l $): 18,463 GDP per capita (current US$): 7,808 Unemployment (ILO estimate): 0.8% Population below poverty line (2015): 7.2% Ease of Doing Business ranking: 21th (out of 190) Procedures to register a business: 5 Cost of business start-up procedures (% of GNI per capita): 3.0% Mobile subscriptions / 100 inhabitants: 186 Internet users as % of population: 67% Broadband subscriptions / 100 inhabitants: 14.52 Demographic Indicators Population (2020 est.): 69.63m Population growth rate (2020 est.): 0.3% Languages: Thai (official, 91%), English is secondary language of the elite Urban population: 35.30m (51% of total) Thailand lage breakdown (2019) Percentage 25% 23.29% 21.20% 20.22% 20% 16.82% 15% 10% 5% 13.61% 4.85% 0% 0-14 15-29 30-44 45-59 60-74 75+ Age (range) Healthcare Indicators INSEAD Healthcare expenditure as % of GDP (2017): 3.75% Healthcare expenditure per capita (2017, current US$): 247.04 USD Human Development Index ranking: 77th (out of 189) Life expectancy at birth: 75.6 years Infant mortality rate: 8.6 deaths/1,000 live births Physician density: 0.81 physicians/1,000 population Hospital bed density: 2.1 beds/1,000 population Private sector share of hospital beds (2018): 27.4% Major causes of death: 1) Heart disease, 2) stroke, 3) lower respiratory infection, 4) Alzheimer's disease, 5) Liver cancer Sources: CIA Factbook, World Bank 38#39Thailand's successful implementation of the universal healthcare leads to a growth in medical tourism Public Healthcare System Overview Thailand's universal healthcare entitles every Thai citizen to essential health services • • Most public hospitals in Thailand are operated by the Ministry of Public Health Rural areas of Thailand are still underserved medically, with lower quality of care and less access (1) Authorities There have been pushes toward decentralization, but they have been faced with resistance, and MOPH still directly controls most aspects of healthcare Financing Thailand's universal healthcare system is largely financed by general government taxation • • • Private Healthcare Options Private hospitals largely complement the public hospitals, especially in larger urban areas of Thailand Private hospitals are regulated by the Medical Registration Division INSEAD Thailand's growing medical tourism industry is driven by private hospitals, and the Thai government is favorably shifting public policy to cater to more medical tourists (2) Investments from conglomerates have been flowing into healthcare in Thailand (e.g. Pruksa Holdings, RSU Group, CP Group, and TCC Group) (2) "The #1 Medical Hub of Asia" Thailand's Board of Investments published a 10-year plan to make Thailand a "Hub of Wellness and Medical Services" with the full support of the government (3) Sources: (1) World Health Organization (WHO); (2) HealthcarelTNews 2019; (3) Thailand Board of Investments 39#40Government actively involved in making and promoting Thailand as the #1 Medical Hub of Asia INSEAD Thailand government is pushing for R&D in technology and innovation Non-Tax Incentives: Foreigners can have 100% ownership of a business, and can acquire permits to own land and bring in skilled workers and experts to work in Thailand. Tax Incentives: the Thailand Board of Investments provides corporate income tax exemptions for 10 years to technology and innovation developments in biotech, nanotech, advanced material technology, and digital technology. There are also exemptions of import duties on various raw or essential materials. The Thai government wants to capitalize on the market development of medical tourism Visas: Thailand is shifting public policy toward creating an environment wherein medical tourists can access the country's services with ease. This includes the loosening of visa restrictions and the creation of smart visas. Private hospitals and conglomerates: Private hospitals are driving Thailand's medical tourism industry, and attracting investments from conglomerates. The private hospitals are expanding and forming partnerships with foreign online platforms or companies Sources: Thailand Board of Investments, HealthcarelTNews 40#41Regulatory landscape, including data privacy laws, is favorable for healthtech startups in Thailand Biotech and digitalization are primed to be the next big areas of development in Thailand Digitalization: Thailand's eHealth strategy largely aims to develop effective IT infrastructure for the country's public health systems, and are actively searching for and working with tech firms to implement these solutions (e.g. VMware partnered with MoPH for IT infrastructure, Block M.D. running test trials for an EHR on blockchain) Biotech: With its already large market position in APAC's medical devices sector, Thailand's incentives are set to attract foreign and domestic projects and investments in the biotech and medical devices sector. Thailand's newly introduced data privacy act, the PDPA, closely following EU's GDPR to protect consumer data privacy Personal Data Protection: The most important part of the PDPA is getting user consent for collecting, using, and sharing data. This law applies to any businesses that collect, process, and/or share personal data in Thailand from users all around the world. In addition, businesses must ensure physical and digital security measures to protect the customer data from unauthorized and malicious access. Impact on startups in healthtech: PDPA requires a little bit more protocol, documentation, and communication, but it does not affect businesses significantly, nor does it create any issues/barriers for new startups. However, if Thailand were to implement additional standards such as the HIPAA Compliance equivalent in Thailand, this may pose barriers and more hurdles for healthtech startups working with patient data. Sources: Thailand Board of Investments, Relentless Data Privacy, SecurePrivacy INSEAD 41#42Key Challenges in the Current Healthcare System include... Urban-Rural Gap Disparities in Insurance Schemes The physician to general population ratio in the rural areas is sparce, as rural health centers cannot compete with urban hospitals in attracting talent with high compensation This gap leads to a less access and lower quality of service for people in rural areas The universal healthcare consists of three schemes, all with its own legal framework and eligibilities, meaning that not all people will have equal access to similar packages of healthcare Growing Costs The general tax funded universal healthcare system is expensive, and changes will need to be made to lower costs especially with an aging population in Thailand Shortage of Healthcare Professionals The MoPH is facing a shortage of registered nurses, leading to higher cost of staffing, lower quality of life for overworked nurses, and a lower quality of care for hospitals that are short staffed Sources: WHO, NIH Increasing costs and shortages of staff will require technological solutions INSEAD 42#43Executive Summary & Key Findings Market Overview Indonesia Vietnam Thailand Philippines#44The Philippines - Key Indicators [Indicators are for year 2019 unless otherwise stated] Economic Indicators GDP (PPP current int'l $): 1,003 bn GDP growth rate: 6.0% GDP per capita (PPP current int'l $): 8,908 GDP per capita (current US$): 3,485 Unemployment (ILO estimate): 2.2% Population below poverty line (2017): 21.6% Ease of Doing Business ranking: 95th (out of 190) Procedures to register a business: 13 Cost of business start-up procedures (% of GNI per capita): 23.3% Mobile subscriptions / 100 inhabitants: 155 Internet users as % of population: 43% Broadband subscriptions / 100 inhabitants: 3.87 Demographic Indicators Population (2020 est.): 109.18m Population growth rate (2020 est.): 1.52% Languages: Filipino (based on Tagalog), English Urban population: 50.98m (47% of total) Philippines age breakdown (2019) Percentage 35% 30.48% 30% 27.53% 19.98% 13.68% 25% 20% 15% 10% 5% 0% 0-14 15-29 30-44 45-59 60-74 75+ Age (range) 6.66% 1.68% Healthcare Indicators INSEAD Healthcare expenditure as % of GDP (2017): 4.45% Healthcare expenditure per capita (2017, current US$): 132.90 USD Human Development Index ranking: 106th (out of 189) Life expectancy at birth: 70 years Infant mortality rate: 20 deaths/1,000 live births Physician density: 0.6 physicians/1,000 population Hospital bed density: 1 bed/1,000 population Private sector share of hospital beds (2016): 53% Major causes of death: 1) Heart disease, 2) Stroke, 3) Lower respiratory infection, 4) Chronic kidney disease, 5) Tuberculosis Sources: CIA Factbook, World Bank 44#45INSEAD The Philippines' healthcare ecosystem is highly fragmented across both public and private health sectors • · . Public Healthcare System Gov't has actively pursued universal health coverage since 2010 but access remains highly inequitable Relatively low quality of care due to limited health facilities relative to growing population, and poor physician adherence to clinical practice Financial risk protection for healthcare remains limited - limited coverage by national social health insurance scheme PhilHealth Fragmented, with more than a thousand autonomous local health systems at provincial, municipal level . Private Healthcare Sector The Philippines' private healthcare sector is extensive & expanding In 2016, the private healthcare sector accounted for 53% of hospital beds in the Philippines (but caters to only about 30% of the population) Private healthcare is widely available in major cities, and generally offers higher quality and faster treatment than public healthcare facilities The Philippines lacks an effective mechanism to regulate the large and fragmented private healthcare sector National Level: Department of Health Develops & enforces national policies, evaluates & delivers tertiary & specialized hospital services Provincial Level: Provincial Departments of Health Tasked with primary & secondary hospital care Municipal Level: Local Health Centres, Stations Tasked with providing primary health care, promotive & preventative health programmes, basic clininal care Sources: WHO Asia Pacific Observatory on Health Systems and Policies - The Philippines Health System Review; Philippines Department of Health 45#46Gov't efforts at universal health coverage and digital health service delivery have had limited success High out-of-pocket health expenditures, particularly on medicines INSEAD National Social Health Insurance (PhilHealth): While the gov't has promised universal health coverage and sought to expand membership of national social health insurance programme PhilHealth, the out-of-pocket share of health expenditure remains the highest among SEA's five largest economies at 54% (compared to 37% in Indonesia and 12% in Thailand). PhilHealth-covered services focus on inpatient care, hence medicines are the main driver of out-of-pocket spending. Fragmented Pharma Retail: Filipinos mostly access medicines through private retail drugstores. Large drugstore chains have most of the market in big cities, while in other municipalities, medicines are mostly obtained from pharmacies operated by local pharmacists and physicians. While the emergence of generic medicine retailers in recent years has provided competition to large drugstore chains in the cities and helped to push prices down, the relative fragmentation of the sector has led to procurement inefficiencies and higher costs. Uneven implementation of gov't digital health efforts, including a health information exchange (HIE) eHealth Strategic Framework & Plan: The Department of Health's eHealth Strategic Framework & Plan (2014 – 2020) envisioned that by 2020, eHealth would enable widespread access to health care services and health information, but implementation has been lacking in part because fragmentation has prevented public healthcare system from leveraging procurement power to promote eHealth. Philippine Health Information Exchange (PHIE): A major issue in the Philippines' fragmented health system is the lack of a health information exchange allowing for the sharing of health data that would allow more efficient provision of private and public healthcare. Currently, health record management continues to follow a provider-centric model and still mostly uses paper records. While implementation of the PHIE, a component of the gov't's eHealth strategy began in 2016, it continues to be in a testing phase. Growing demand for imaging & diagnostic equipment to address chronic diseases Medical Equipment Demand Patterns: Notable trends include: (1) a shift in demand towards the value segment to contain healthcare costs, and (2) increased demand for imaging & diagnostic equipment resulting from rise in chronic diseases such as diabetes, cancer and cardiovascular diseases. Sources: Various sources including WHO Asia Pacific Observatory on Health Systems and Policies; Foundation for Media Alternatives ("Health Information Exchanges & Data-Intensive Systems") 46#47Healthtech ventures must manage the Philippines' comprehensive data privacy measures INSEAD Comprehensive data privacy measures are enforced by a relatively active independent watchdog Data Privacy Act (DPA) 2012: The comprehensive DPA was passed in 2012 "to protect the fundamental human right of privacy, of communication while ensuring free flow of information to promote innovation and growth". It has extraterritorial application, applying not only to businesses located in the Philippines, but also when equipment based in the Philippines is used for processing data, as well as to the processing of Philippines' citizens' personal information, regardless of where they reside. The law has relatively extensive requirements for businesses, including mandatory data protection officers and breach reporting rules, as well as an annual written report documenting all security incidents and personal data breaches. Infringement penalties extend up to six years' imprisonment. National Privacy Commission (NPC): The NPC is the independent body responsible for administering the DPA and is vested with a relatively extensive range of powers including receiving complaints, instituting investigations on data privacy incidents, and compelling entities to abide by its orders in matters affecting data privacy. For instance, in Feb 2020, it directed that Grab Philippines cease its selfie-verification and in-vehicle audio and video recording systems due to data privacy deficiencies. It also shut down a number of online lending apps in Oct 2019 because they had violated the DPA by publicly sharing information on defaulting borrowers to shame them. Covid-19 pandemic has prompted efforts to clarify how data privacy applies to healthcare DPA Implications for Contact Tracing During Covid-19 Pandemic: In Aug 2020, Interior Secretary Eduardo Año reportedly acknowledged that the DPA posed a challenge in contact tracing during the Covid-19 pandemic, as it limited the types of information hospitals could collect from patients. The Philippines' business sector (as represented by major business associations including the Philippine Chamber of Commerce and Industry) also publicly called for the temporary suspension of the DPA in order to reduce the expenses involved in contact tracing. The NPC subsequently clarified that the DPA should not prevent hospitals from sharing patient information with the relevant authorities, but advised against publicly naming patients even for contact tracing efforts, due to the risk of possible harassment or humiliation. Department of Health (DOH) and NPC Collaboration on Telemedicine Framework: In Apr 2020, the DOH and NPC jointly developed a framework for telemedicine services in an effort to decongest hospitals and provide access to healthcare during the Enhanced Community Quarantine (i.e. lockdown). It established that licensed healthcare providers conducting medical consultations over the phone, chat, SMS, and other audio and visual-conferencing platforms were formally considered telemedicine services in the country, and were allowed to issue electronic case reports and prescriptions. Sources: Various sources including Philippines National Privacy Commission; Philippine Department of Health; GrowYourBusiness.org; Manila Bulletin ("Business sector suggests suspension of Data Privacy Law") 47#48Key Challenges in the Current Healthcare System include... Maldistribution of Healthcare Resources Brain Drain Rising Healthcare Costs Fragmented, Inadequate Governance Framework Healthcare resources are heavily concentrated in the more economically developed island of Luzon Luzon houses ~53% of the population, but has 65% of hospital beds in the Philippines Geographically isolated and economically disadvantaged areas (e.g. in Mindanao) suffer from a shortage of healthcare professionals and facilities - Mindanao has only one bed per 4,606 people compared to one-per-591 in Metro Manila. The Philippines is a major exporter of healthcare professionals (6th largest contributor of doctors and top contributor of nurses to OECD countries), but struggles to ensure adequate availability within the country, with an estimated shortage of 23,000 nurses in the Philippines Push factors include low salary and poor working conditions, but tele-health offers potential to connect this diaspora of healthcare professionals with needs back in the Philippines Healthcare costs are rising significantly - Willis Towers Watson estimated medical costs net of general inflation would increase by 4.9% in the Philippines in 2020 Financial protection from PhilHealth remains limited, resulting in a shift in demand towards the value segment (both in medicines and medical equipment) to contain healthcare costs The Philippines lacks a centralized healthcare resource allocation authority, with the public healthcare system fragmented between the demand-side (Department of Health, local government units) and the financing supply-side (PhilHealth), resulting in procurement inefficiencies and shortages in medicines and equipment. The fragmented nature of the healthcare system has resulted in inefficiencies and misallocation of resources Sources: Various sources including WHO Asia Pacific Observatory on Health Systems and Policies; PwC ("Embracing New Healthcare Technologies that Empower Filipinos"), Japan Times article ("Brain drain: Philippines sends nurses around the world but lacks them at home") INSEAD 48#49T Appendix INSEAD#50Other Useful Reports & Resources Report Name Source The USD 320 Billion Healthcare Challenge in ASEAN Solidiance APAC Health Tech Investment Landscap- FY2019 Southeast Asia: The New Emerging Healthcare Market Challenge Galen Growth Link https://www.solidiance.com/insights/white-papers/the-usd-320-billion- healthcare-challenge-in-asean/download?token=q9ZWvrYXJG https://andhealth.com.au/wp-content/uploads/2020/01/Galen-Growth- HealthTech-Investment-Landscape-FY2019-Public.pdf Economist Intelligence Unit https://www.eiu.com/public/topical_report.aspx?campaignid=seasiahealt hcare Deloitte Healthcare and Life Sciences Predictions 2020: Southeast Asia Supplement EMPEA Data Insight Southeast Asia - 2020 Southeast Asia Exit Landscape Deloitte Centre for Health Solutions EMPEA INSEAD A NEW FRONTIER The Republic of Indonesia Health System Review WHO https://www2.deloitte.com/content/dam/Deloitte/sg/Documents/life- sciences-health-care/sea-lshc-predictions-2020-sea-supplement- noexp.pdf Offline https://www.insead.edu/sites/default/files/assets/dept/centres/gpei/docs/ golden-gate-ventures-insead-sea-exit-landscape.pdf?t=1006&t=1006 https://apps.who.int/iris/bitstream/handle/10665/254716/9789290225164 -eng.pdf;sequence=1 INSEAD 50 50#51Advisors/Interview Sources Name Role Company Jeff Stolte Senior Partner Providence Ventures (PV) Valerian Fauvel Non-Executive Director Insitor Partners (IP) Steve Okun Senior Advisor Aki Roslan Principal Company Description PV is the VC arm of Providence Healthcare, a $25B US organization comprised of 50+ hospitals. PV is currently investing their 2nd $150M fund, and looks for both opportunistic investments and investment opportunities that align with Providence's strategic and operational goals IP is a SGP-based VC focused on startups in emerging Asian markets. Their goal is to support the development of markets inclusive of low-income communities McLarty Associates & EMPEA McLarty helps clients manage policy & government issues around the world Strategic Year Holdings Limited Strategic Year Holdings Limited ("Strategic Year") is a privately held investment company (Private equity and real estate) active in SEA. INSEAD 51 54#52INSEAD The Business School for the World® Europe Asia Middle East

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