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Investor Presentaiton

ADVANTAGES OF STEROIDS IN RETINAL DISEASES Q Inflammation plays a critical role in the etiology of both DME and non-infectious uveitis - In diabetes, hyperglycemia causes chronic, low-grade inflammation alimera Uveitis involves approximately 30 inflammatory disorders characterize by ocular inflammation Q Inflammation is multi-factorial; requiring more than just anti-VEGF - Despite monthly treatment 32-66% of patients still have persistent DME that doesn't go away] One third of patients discontinue standard of care in any given year leading to undertreatment² Q Local delivery of a steroid for non-infectious uveitis avoids the side effects of systemic steroids NOTES: 1. DRCR. net Protocol T data 2. https://www.healio.com/news/ophthalmology/20220504/iris-registry-onethird-of-patients-with-dme-discontinue-antivegf-treatment Nasdaq: ALIM 9
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