Investor Presentaiton

9M'22 Highlights United States 'Santander US combines a strong depositary base in the Northeast with its nationwide auto finance, wealth management and corporate banking capabilities' Branches 484 00 MA Employees 14,705 Total customers (mn) 4.6 Digital customers (mn) 1.0 • Customer loans (€ bn) 121 Customer funds (€ bn) 111 Strategic priorities ■■ Positioned to deliver above cost of capital returns across core businesses Refocus the US on our market leading consumer franchise Simplification: disciplined capital allocation. Continue focusing our resources and capital on products and services where we can achieve scale and profitable growth (Auto, CRE, CIB) Underlying attributable profit (€ mn) 1,489 • Synergies from 2021 strategic investments (Crédit Agricole / Amherst Pierpont / SC USA minority interests)² ROTE¹ 18.8% Santander (1) Adjusted ROTE: adjusted based on Group's deployed capital calculated as contribution of RWAS at 12%. Using tangible equity, ROTE is 10.3%. (2) Acquisition of SC USA minority interest closed on 31 January 2022. Acquisition of Amherst Pierpont received regulatory approval in April 2022. Customer loans: Gross loans excluding reverse repos. Customer funds: customer deposits excluding repos + marketed mutual funds. More information at https://www.santander.com/en/about-us/where-we-are/santander-us 25

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