Investor Presentaiton

SNS812 Virus Inhibition - in vivo ONENESS Post-exposure Treatment Showed Significant Inhibition of Viruses hACE2 Post-exposure DO D1 D2 Viral titer Original strain(B) P = 0.026 analysis (Lung) Post-exposure DO D1 D2 Viral titer analysis (Lung) hACE2 Delta strain(B.1.617.2) P=0.018 P = 0.004 P = 0.038 P = 0.012 Virus copies/ug (Log 10) 6 PFU/g (Log 10) 2 P = 0.035 Control SNS812 Viral RNA reduced 96.2% Control SNS812 Infectious virions reduced 96.1% -Data submitted for publication- 100 Relative virus RNA level (%) 10- PFU/g (Log 10) N C T C T 2 doses 3 doses Viral RNA 2 doses reduced 80% 3 doses reduced 90% C T C T 2 doses 3doses Infectious virions 2 doses reduced 90.5% 3 doses reduced 93% | 31

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