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Investor Presentaiton

Company overview Financial performance Oncology Financial review 2022 priorities Appendix References Innovation: Pipeline overview Innovation: Clinical trials Abbreviations Immunology Ophthalmology Neuroscience Respiratory Disease Cardio-Renal Global Health Biosimilars RydaptⓇ - Multi-targeted kinase inhibitor NCT03591510 (CPKC412A2218) Acute myeloid leukemia, pediatrics Phase 2 Indication Phase Patients 20 Primary Outcome Measures Arms Intervention Target Patients Occurrence of dose limiting toxicities Safety and Tolerability Chemotherapy followed by Midostaurin Newly diagnosed pediatric patients with FLT3 mutated acute myeloid leukemia (AML) Read-out Milestone(s) 2026 Publication TBD 59 Investor Relations | Q2 2022 Results NOVARTIS | Reimagining Medicine
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