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Investor Presentation

142 Investor presentation First six months of 2022 Net profit has been converted to cash and returned to shareholders Cash conversion and allocation (2021) DKK billion 48 48 50 (100%) (100%) 41 (86%) 40 40 Dicerna pharmaceuticals 19 30 30 20 20 10 0 Net profit 29 22 22 Novo NordiskⓇ Strategic capital allocation priorities Business development investments to enhance R&D pipeline CAPEX investments to meet demand including R&D pipeline Free cash flow Cash return Share buyback Dividends Deliver competitive capital allocation to shareholders Continued share buybacks and dividends Financial flexibility within current credit ratings Moody's: A1 since 2012, S&P Global: AA- since 2013 Net debt to EBITDA ratio around zero Mainly debt finance major business development projects • 2021 bond issuance at an all-inclusive interest rate of ~0% Note: Cash used for the acquisition of Dicerna Pharmaceuticals was 18,282 million DKK per note 5.3 of the 2021 Novo Nordisk Annual Report R&D: Research and Develoment; CAPEX: Capital expenditure; EBITDA: Earnings before interest, taxes, depreciation and amortisation
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