Investor Presentation First Nine Months of 2023 slide image

Investor Presentation First Nine Months of 2023

11 Investor presentation First nine months of 2023 Generating evidence with the semaglutide molecule beyond glycaemic control and weight loss Serious chronic diseases are associated with Millions of patients are affected globally ILLUSTRATIVE PAD AD diabetes and obesity MASH Diabetes 537 million¹ Obesity >764 million² CKD G₁₂O CVD HF G₁ CKD: 700 million³ ت | Novo NordiskⓇ Novo Nordisk is generating evidence to adress the medical unmet need in subpopulations FLOW I MASH: ~25 million4 I ESSENCE | CVD: ~520 million 5 SELECT SOUL HF: ~64 million 6 STEP HFPEF STEP HFPEF-DM PAD: ~200 million? STRIDE T I Alzheimer's Disease: ~85 million8 evoke evoke+ 1International Diabetes Federation: Diabetes Atlas 10th edition, 2021; 2World Diabetes Atlas 2022; ³Carney EF. Nat Rev Nephrol 2020;16:251; 4Estes C et al. Hepatology, 2018; 5Roth GA et al. J Am Coll Cardiol 2020; 6Groenewegen A et al. Eur J Heart Fail 2020;22:1342-13561; Fowkes FG et al. Lancet 2013; 8WHO, Dementia key facts 2022 ASCVD: Atherosclerotic cardiovascular disease; MASH: Metabolic dysfunction-associated steatohepatitis; CVOT: Cardiovascular outcome trial; T2D: Type 2 diabetes; CKD: Chronic kidney disease; PAD: Peripheral arterial disease; HF: Heart failure; HFpEF: Heart failure with preserved ejection fraction, HFPEF-DM; Heart failure with preserved ejection fraction with Diabetes; s.c.: Subcutaneous.
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