Investor Presentation - First Six Months of 2021 slide image

Investor Presentation - First Six Months of 2021

69 Investor presentation First six months of 2021 Novo NordiskⓇ Haemophilia is a rare disease with severe unmet medical needs and the market is highly competitive Number of Low diagnosis and treatment rates within haemophilia DKK billion Sales of recombinant haemophilia products people (000) 500 400 300 200 100 0 People with haemophilia Diagnosed Haemophilia A Haemophilia B 40 40 30 30 20 20 10 0 Inhibitor 2016 2020 2016 Haemophilia with inhibitors NovoSevenⓇ Coagil VII Obizur¹ 2020 Haemophilia A 2016 NovoEight® 2020 Haemophilia B RefixiaⓇ/RebinynⓇ Advate/Adynovate Idelvion Kogenate/Kovaltry/Jivi Rixubis Feiba² Hemlibra³ Xyntha/Refacto Alprolix Eloctate/Elocta Benefix Helixate/Afstyla Hemlibra Note: The inhibitor segment includes acquired haemophilia patients, patients with low titre inhibitors or with transient inhibitors, and patients on immune tolerance induction. Source: World Federation of Haemophilia (WFH) - Annual survey 2018; WFH: Closing the gap - achieving optimal care, Haemophilia 2012. 1 Obizur only indicated for acquired haemophilia; 2 Plasma-derived; 3 Part of the Hemlibra sales is used for treatment of haemophilia A patients in 2020 Source: Company reported sales and Evaluate
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