Investor Presentaiton
Robust Pipeline Across Novel Therapeutics - Oncology
4 commercialized, 1 in NDA, 4 in pivotal trials and 11 assets in clinical stage
Status
Products
Target (s)
Modality
Therapeutic Area
Commercial Rights
Pre-clinical
IND Approved
Phase 1
Phase 2
Pivotal Phase
2/ Phase 3
NDA
Launched
Lilly
TYVYTⓇ (sintilimab injection)
PD-1
Monoclonal antibody
Oncology
Worldwide
BYVASDAⓇ (bevacizumab injection)
VEGF-A
Monoclonal antibody
Oncology
Lilly
HALPRYZA® (rituximab injection)
CD20
Monoclonal antibody
Oncology
Worldwide
Worldwide
Incyte)
IBI-375 (Pemigatinib)
FGFR1/2/3
Small molecule
Oncology
Mainland China, HK, Taiwan, Macau
2L MCCA (Approved in Taiwan, NDA accepted in mainland China and HK);
1L CCA (joined Incyte's global Phase 3 trial)
Drug-resistant chronic myeloid leukemia (CML), NDA accepted in China
IBI-348 (Olverembatinib)
BCR-ABL/KIT
Small molecule
Oncology
Mainland China, HK, Taiwan, Macau
GIST
Ph + ALL
IBI-310
CTLA-4
Monoclonal antibody
Oncology
Worldwide
Incyte
IBI-376 (Parsaclisib)
РІЗКО
Small molecule
Oncology
Mainland China, HK, Taiwan, Macau
IBI-326
BCMA CAR-T
Cell therapy
Oncology
Worldwide
AnHeart
Therapeutics IBI-344 (Taletrectinib)
ROS1/NTRK
Small molecule
Oncology
Mainland China, HK, Taiwan, Macau
Adjuvant melanoma
2L Cervical cancer
11 HCC
Lr/r FL and MZL (China).
Myelofibrosis (Incyte's global Phase 3)
r/r multiple myeloma
↑ ROS1+ NSCLC (1L+2L).
NTRK+ Solid tumors
MDS (China)
MDS (US)
r/r AML (China)
Phase 1b and Phase 2 for multiple cancer types in plan
Advanced malignancies (China)
Advanced malignancies (US
Phase 1b for multiple cancer types
IBI-188
CD47
Monoclonal antibody
Oncology
Worldwide
IBI-110
LAG-3
Monoclonal antibody
Oncology
Worldwide
IBI-322
PD-L1/CD47
Bispecific antibody
Oncology
Worldwide
Lilly
IBI-318
PD-1/PD-L1
Bispecific antibody
Oncology
Mainland China, HK, Macau
Hanmi
IBI-315
PD-1/HER2
Bispecific antibody
Oncology
Worldwide
IBI-939
TIGIT
Monoclonal antibody
Oncology
Worldwide
IND approved (US)
Lilly
IBI-321
PD-1/TIGIT
Bispecific antibody
Oncology
Mainland China, HK, Macau
Lilly
IBI-319
PD-1/4-1BB
Bispecific antibody
Oncology
Mainland China, HK, Macau
IBI-323
LAG-3/PD-L1
Bispecific antibody
Oncology
Worldwide
IBI-102
GITR
Monoclonal antibody
Oncology
IBI-101
OX40
Monoclonal antibody
Oncology
Worldwide
Worldwide
Listed drugs
Biologics
Small molecules
Clinical progress in the U.S.
Robust oncology pipeline with 20 clinical stage assets, covering monoclonal antibodies, bispecific antibodies, CAR-T and small
Innovent
molecules
Confidential
Copyright©2021 Innovent Biologics
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