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Investor Presentaiton

5 Growth & Launch Products Revenue Grew +19% at CER in FY22 H1 (M) GI MM RARE DISEASES 0 PLASMA-DERIVED THERAPIES (PDT) IMMUNOLOGY ONCOLOGY NEUROSCIENCE Takeda OTHER Entyvio vedolizumab TAKHZYRO (lanadelumab-flyo) injection +31% +17% GROWTH & LAUNCH PRODUCTS ALOFISEL +33% HyQvia GAMMAGARDLIQUID [Immune Globulin Intravenous (Human)] 10% Human Normal Immunoglobulin (0%) Recombinant Human Hyaluronidase Cuvitru Immure Globulin Subcutaneous Human 20% IMMUNOGLOBULIN +17% LIVTENCITY™ tablets (maribavir) 200 New Launch Flexbumin (Human Albumin) HUMANALBUMIN ALBUMIN +8% ALUNBRIG BRIGATINIB 30 mg TABLETS +41% EXKIVITY mobocertinib 40 mg capsules New Launch ウイルスワクチン COVID-19 Vaccine spikevax Suspension for Intramuscular Injection (JP) ヌバキソビッド筋注 NuvaxovidⓇ (JP) Total FY2022 H1 Revenue 759.8B (USD 5.3B)¹ (+19% growth at CER) Ninlaro IclusigⓇ Adcetris (ex-N. America) Leuprorelin Advate/AdynoviⓇ OTHER KEY PRODUCTS Takecab/VocintiⓇ Gattex/RevestiveⓇ VonvendiⓇ Elaprase® VprivⓇ ReplagalⓇ(EU,JP) GlassiaⓇ AralastⓇ VyvanseⓇ Trintellix (US,JP) AzilvaⓇ (JP) Zejula (UP) CabometyxⓇ (JP) All growth rates indicate FY2022 H1 revenue growth at CER 1. Convenience translation at an exchange rate of 1USD = 144.71 JPY, the Noon Buying Rate certified by the Federal Reserve Bank of New York on September 30, 2022.
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