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Investor Presentaiton

Novo Nordisk Annual Report 2023 OBESITY Introducing Novo Nordisk Strategic Aspirations Risks Management Consolidated statements Additional information Controlled launches for market-leading obesity therapy GLOBAL PREVALENCE OF OBESITY IN ADULTS (millions) - Obesity 2,000 Surging demand, limited supply and unprecedented global media attention on our ground-breaking obesity treatment, WegovyⓇ, have brought significant challenges - as well as exciting long-term opportunities. Demand for WegovyⓇ is still growing strongly in the US, its first launch market, and we have taken proactive steps to conduct controlled and limited roll-outs in other major markets, with the goal of reaching the patients in greatest need of the therapy despite ongoing supply constraints. "Novo Nordisk is also reserving a share of Wegovy supply in each new launch market for patients who cannot afford to pay for the product out of pocket." In the UK, for example, WegovyⓇ is now available in specialist National Health Service weight management services for people who meet strict criteria, or else privately through a registered healthcare professional. UK physicians are being urged to prescribe responsibly and Novo Nordisk is also reserving a share of WegovyⓇ supply in each new launch market for patients who cannot afford to pay for the product out of pocket. The success of WegovyⓇ, which builds on our experience with our first-generation GLP-1-based obesity product SaxendaⓇ, means that Novo Nordisk has captured most of the growth and gained a clear leadership position in the obesity market. The sector remains extremely dynamic, with new players lining up to enter the space amid a growing appreciation that medicines tackling obesity have the potential to boost public health and cut long-term healthcare costs. Globally, the number of people living with obesity has almost tripled since 1975 and is set to reach over 1.2 billion adults by 2030. The causes of obesity are complex and its consequences far-reaching because, so often, it puts people on a path to other diseases - not only diabetes, but also heart and liver diseases, cancers and many more. Today, only one in 10 people living with obesity seek professional medical help - and only one in five of those receive treatment with a weight management medication. But attitudes are changing fast. The past two years have been characterised by a growing understanding among both the medical community and the public of the critical need to treat obesity, while an increasing number of people living with the disease are actively seeking support. We want to understand more about their journey and how we can continue to help them maintain their long-term progress towards better health. 1,600 1,532 1,246 1,200 1,007 813 800 400 0 2020 2025 2030 2035 Source: Obesity Atlas, 2023. OBESITY SALES (DKK billion) ‣ Sales as reported Growth at CER 50 40 30 20 55% 3% 10 84% 154%) 0 2020 2021 2022 2023 32
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