Roche Pharmaceutical Development and Sales Overview

YTD exchange rate swings Negative impact driven by the EUR, JPY and other Europe, partially offset by USD Roche CER sales growth YTD Sep 2022 VS. YTD Sep 2021 -1.2p +1.7% +0.1p +1.9p -0.1p -1.0p +0.1p -0.7p +0.8% CHF sales growth YTD Sep 2022 VS. YTD Sep 2021 CER EUR APAC USD LATAM JPY Other Other Europe CHF 47 CER = Constant Exchange Rates (avg full year 2021)

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