Investor Presentation Q1-Q3 2020

80 Investor presentation First nine months of 2020 Insulin market size and volume share of growth and market share in International Operations Insulin market share and market size (DKK billion) Market growth A Market share Total 49% Long- Acting 35% Fast- 59% 15 acting Premix 75% 8 27 49% Human 8 Novo Nordisk Competitors Source: IQVIA, Aug 2020, LHS graph - Value, RHS Graph - Volume, MAT, all countries; NN: Novo Nordisk 59 59 Insulin volume: Share of growth and market share Novo NordiskⓇ 80% 5% +0.8% 10% 66% 8% 60% 7% +1.2% 50% 6% 40% 6% +0.9% 20% 4% +1.4% 0% Aug -1.1% -0.3% 4% 2% 0% Aug 2020 2017 NN market share -Market growth NN share of growth NN growth

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