Investor Presentation Full Year 2021 slide image

Investor Presentation Full Year 2021

115 Investor presentation Full year 2021 North America Operations at a glance. NAO WA 30 56 56 48 20 10 0 2019 2030 Diabetes trend in population Diabetes market by value and Novo Nordisk market share Million DKK billion 70 13% 600 60 18% 50 40 Novo Nordisk reported sales Full year 2021 Sales (mDKK) Growth² 80% Total GLP-13 37,491 25% Long-acting insulin4 6,990 (15%) 60% Premix insulin5 691 6% 400 GLP-1 36%¹ Fast-acting insulin 6,784 (6%) 40% Human insulin 1,599 8% 63 Total insulin 16,064 (9%) Insulin 2%1 200 Other Diabetes care? 950 (10%) 20% Diabetes care 54,505 12% 12%1 OAD Obesity care8 5,283 57% 0 0% Nov 2045 2016 Population with diabetes Diabetes growth rate GLP-1 MS Insulin MS Nov 2021 OAD MS Diabetes & Obesity 59,788 15% care Biopharm⁹ Total 7,475 6% 67,263 14% International Diabetes Federation: Diabetes Atlas 1th Edition 2000 and Diabetes Atlas 9th Edition 2019 1 CAGR calculated for 5-year period Competitor insulin value market shares, as of Nov 2021: Novo Nordisk 42%, Eli Lilly 30% and Sanofi 27%; Competitor GLP-1 value market shares, as of Nov 2021: Novo Nordisk 52%, Eli Lilly 45% and AstraZeneca 4% OAD: Oral anti-diabetic; MS: Market Share; Source: IQVIA MAT, Nov 2021 value figures 2 At constant exchange rates; 3 Comprises Victoza®, OzempicⓇ, and RybelsusⓇ; 4 Comprises Tresiba®, XultophyⓇ and Levemir®; 5 Comprises NovoMixⓇ; 6 Comprises FiaspⓇ and NovoRapid®; 7 Comprises Novo NormⓇ and needles; 8 Comprises SaxendaⓇ and Wegovy ® 9 Comprises primarily NovoSeven®, NovoEight® Esperoct®, NovoThirteenⓇ, Refixia®, Norditropin®, VagifemⓇ and Activelle®
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