Q4 2021 Results slide image

Q4 2021 Results

Participants Company overview Pharmaceuticals Financial performance Oncology Innovation: Pipeline overview Financial review Conclusion Strong FY operational performance from growth drivers Key growth driver sales FY 20211 Driving portfolio rejuvenation Appendix Innovation: Clinical trials Sales USD Million Growth vs. PY Growth vs. PY USD Million CC Key growth drivers 52% of IM sales, growing 25% vs. PY Entresto sacubitrill/valsartan 3,548 1,051 40% AimovigⓇ 52% Cosentyx 4,718 723 17% MayzentⓇ (secukinumab) Piqray® zolgensma 1,351 431 46% 44% Kesimpta 372 357 nm (ofatumumab) 35% PROMACTA (eltrombopag) 2,016 278 15% JAKAVI® 1,595 256 16% 27% KesimptaⓇ XiidraⓇ LutatheraⓇ KymriahⓇ KisqaliⓇ ruxolitinib KISQALI 937 250 36% ribociclib ILARIS 1,059 186 22% (canakinumab) Xolair 1,428 177 12% Omalizumab SUBGYGARDOS OS llarisⓇ ZolgensmaⓇ JakaviⓇ Tafinlar+Mekinist® Promacta® EntrestoⓇ Tafinlar +Mekinist 1,693 151 8% beb KYMRIAH 587 113 22% (tisagenlecleucel) fin MAYZENT. 281 111 CosentyxⓇ Other² FY 2018 FY 2019 FY 2020 FY 2021 65% (siponimod) tablets nm - not meaningful 1. Innovative Medicines division. 2. Includes Xolair®, Beovu ®, Adakveo®, Tabrecta Ⓡ, Luxturna®, Enerzair ®, Atectura ®, LeqvioⓇ and ScemblixⓇ. Constant currencies (cc), core results and free cash flow are non-IFRS measures. An explanation of non-IFRS measures can be found on page 49 of the Condensed Financial Report. 52 Investor Relations | Q4 2021 Results U NOVARTIS | Reimagining Medicine
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