Investor Presentation First Nine Months of 2023

149 Investor presentation First nine months of 2023 Operating profit expected to be negatively impacted by currencies in 2023, partly countered by net financials Avg. FY 2022 vs. Avg. FY 2021 Exp. Avg FY 2023'vs. FY 2022 10% Hedged 0% -10% USD/DKK CNY/DKK JPY/DKK CAD/DKK GBP/DKK 12% -8% Non- hedged -28% -48% RUB/DKK INR/DKK ARS/DKK BRL/DKK TRY/DKK Novo NordiskⓇ • FY 2022 Positive FX impact on operating profit of 7.6 bDKK Negative FX impact on net financials of -4.7 bDKK Foreign exchange net gain of 2.9 bDKK FY 2023 outlook Currency impact on Operating profit is expected to be -7%-points Net financial items is expected to be a gain of around DKK 1.6 billion mainly driven by gains on USD and JPY hedging contracts. 1 Year-to-date realised data and remainder expected flat currency development based on the spot rate as of 26 October 2023 USD: United States dollar; DKK: Danish Kroner; CNY: Chinese yuan renminbi; JPY: Japanese yen; CAD: Canadian Dollar; GBP: British pound sterling; RUB: Russian Ruble; INR: Indian rupee; ARS: Argentine Peso; BRL: Brazilian Real; TRY: Turkish New Lira

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