AbCellera Investor Conference Presentation Deck

JPM HEALTHCARE CONFERENCE 2024 COPYRIGHT © ABCELLERA 12 OUR ENGINE: T-CELL ENGAGER PLATFORM Expanding the target space: Discovery platform enables generation of diverse and highly specific pMHC binders. Example molecules 2 pMHC + Fab side view 1 Heavy chain PMAGE-A4230-239 MHC-I Light chain 3 Tumor-cell 100₁ killing (%) 50- 400₁ TNFa (pg/mL) 300- 200- IFNY (pg/mL) 100- 0- 2x105- 1x105- -6 1 -4 O [bispecific] (nM) -2 2 -6 -4 2 -2 2 -6 -4 3 -2 O NL 2 MAGE-A4+ cells AbCellera molecules Molecule R MAGE-A4 knockout cells AbCellera molecules O Molecule R

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