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Investor Presentation

M&A accelerates our expansion, elevates our presence Our strategic acquisitions meet strict criteria: o Technology leadership o Strengthens, expands Repligen's market position o Underinvested in a key area o Strong revenue growth, margins in line with or above corporate average o Potential to be accretive to adjusted EPS in first full yet-acquisition 2014-2019: o Built out Filtration, established Analytics franchises 2020-2023: o Built out Fluid Management o Strengthening all franchises R REPLIGEN Areas of Investment to Accelerate Growth Commercial Operations Acquisition C Technologies May 2019 Highly differentiated, in-line, real-time, fast and accurate measurement ARTESYN Biosolutions December 2020 Premier integrated systems for filtration and chromatography Polymem S.A. June 2021 World class hollow-fiber; immediately expanded HF capacity 3x-4x Avitide Inc. Sept. 2021 Analytics R&D Leading-edge content player; largest most diverse ligand library, gene- therapy affinity resin focus Filtration Chromatography Proteins & Affinity Resins 14
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