Semaglutide Weight Management and Cardiovascular Risk Reduction slide image

Semaglutide Weight Management and Cardiovascular Risk Reduction

The Kansas City Cardiomyopathy Questionnaire, a patient reported outcome, was primary endpoint in the STEP HFPEF trial Disease Symptoms Symptom domains Kansas City Cardiomyopathy Questionnaire¹ Function limitations Quality of life Functional limitation domains Quality of life domain Self efficacy Stability Symptom frequency Symptom burden Physical limitations Social limitations QoL score Dual primary endpoint: KCCQ clinical summary score KCCQ score interpretation² Health status Score 0 to 24 Very poor to poor Poor to fair 25 to 49 50 to 74 Fair to good 75 to 100 Good to excellent 1 Adapted from: Spertus JA. et al. JACC 2020; 76: 2379-2390; Kelkar AA et al. JACC Heart Fail 2016;4:165-175; Nassif ME et al. Circulation 2019;140:1463-1476 2. Enright PL. et al. Respir Care 2003; 48: 783-785. 2 Spertus JA, et al. JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 Nov 17;76(20):2379-2390. HFPEF: Heart Failure with preserved ejection fraction; KCCQ: Kansas City Cardiomyopathy Questionnaire
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