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Investor Presentaiton

119 Investor presentation Full year 2022 Insulin market size and volume market share in EMEA Insulin market share and market size (DKK billion) Total 48% Long- acting 41% Fast- 55% 12 acting 73% Premix 3 19 43% Human 3 Novo Nordisk Competitors Market growth A Market share 60% 37 1.5% +0.1% 3.7% +1.2% 40% EMEA Insulin volume: Market share 10% 47% 7% 4% 3.1% -0.7% 20% -7.6% 0.1% ал -1% 1% -1% 0% -2% Nov Nov 2019 NN market share 2022 -7.5% -0.7% Market growth (right axis) -NN growth (right axis) Source: IQVIA, Nov 2022, LHS graph - Value, RHS Graph - Volume, MAT, Europe, Middle East & Africa, Share of growth not depicted due to too high numbers; NN: Novo Nordisk

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