Investor Presentation First Nine Months of 2022

111 Investor presentation First nine months of 2022 Diabetes market share and market growth in International Operations Diabetes market growth and Novo Nordisk market share 160% 120% 80% 40% 0% Aug Diabetes market size and growth DKK billion 40% ~14% 6 10 207 10 182 30% 21% 20% 14% 38% 10% ~21% 26% 26% 25% 0% Aug 2022 Aug Aug Novo Nordisk AZ Others 2021 2022 Novo Nordisk Competitors 2019 -NN market share Market growth (right axis) NN share of growth NN growth (right axis) Source: IQVIA, Aug 2022, Value, MAT, all countries; NN: Novo Nordisk; AZ: Astra Zeneca Novo NordiskⓇ

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