Retail Banking Performance Update

Mexico (EUR mn) Change Q1'21 Q2'21 Q3'21 Q4'21 Q1'22 Q2'22 Q3'22 Q4'22 Q4'22/Q3'22 2021 Change 2022 2022/2021 Net interest income 661 678 705 730 753 853 950 1,009 +6.2% 2,773 3,565 +28.6% Net fee income 204 210 203 211 245 283 303 309 +2.0% 828 1,140 +37.7% Gains (losses) on financial transactions and other (6) (16) 5 (30) (17) (22) (37) (7) -81.5% (48) (82) +73.0% Total revenue 858 872 913 910 982 1,115 1,216 1,311 +7.8% 3,553 4,623 +30.1% Operating expenses (373) (379) (425) (466) (432) (498) (537) (609) +13.3% (1,643) (2,076) +26.4% Net operating income 485 493 488 444 549 617 679 702 +3.4% 1,910 2,547 +33.3% Net loan-loss provisions (228) (204) (213) (146) (183) (184) (188) (233) +23.6% (791) (788) -0.3% Other gains (losses) and provisions (5) (6) (1) (6) (26) (26) (38) (3) -93.0% (19) (94) +386.4% Underlying profit before tax 253 282 274 292 340 407 452 466 +3.2% 1,100 1,665 +51.3% Underlying consolidated profit 192 217 227 243 257 308 340 352 +3.4% 878 1,257 +43.3% Underlying attributable profit 177 200 210 228 249 297 328 339 +3.4% 816 1,213 +48.6% Santander 41

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