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LOVEVOLUS 53 JEUVEAU EXTRA- STRENGTH PHASE II De ADVERSE EVENT SUMMARY PraB ES 40U N=51 OnaB 20U N=50 PraB 20U N=53 # EVENTS (N=36) ALL ADVERSE EVENTS 8 (22.2%) 12 (33.3%) 16 (44.4%) DRUG RELATED ADVERSE EVENTS 3 2 DURATION STUDY SAFETY # SUBJECTS WITH AES (N=26) ADVERSE EVENTS ALL ADVERSE EVENTS 7 (13.7%) 11 (22.0%) 8 (15.1%) DRUG RELATED ADVERSE EVENTS 2 2 3 Drug Related Adverse Events PraB ES 40U-headache, forehead discomfort, eyelid ptosis OnaB 20U-headache, headache • PraB 20 U-headache, headache, vasovagal 19

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