Investor Presentaiton
Estetrol is an environmentally-friendly estrogen
Ethynyl estradiol (EE)
97% of current marketed Combined
Oral Contraceptives are based on EE
Known as a major Endocrine
Disrupting Chemical
VS
Estetrol (E4)
ā Insignificant endocrine disruptor
effects, whether in aquatic
organisms or organisms living in the
sediment
Amount of biologically active
Estetrol released in the wastewaters
after human use expected to be
minimal
ā Does not accumulate in living
organisms
Likely to dissipate rapidly from water
d sediments
66 All biotests carried out
show without ambiguity
that the endocrine
disruptor effects of
Estetrol are insignificant
in comparison with those
observed for natural
or synthetic estrogens,
whether in aquatic
organisms or organisms
living in the sediment.
Prof. Patrick Kestemont, President of the
Research Institute Live, Earth & Environment,
University of Namur, Belgium
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