Charles River - JP Morgan Conference Presentation

Leading, global, non-clinical drug development partner with a mission to create healthier lives ~21,500 global employees >2,000 scientific professionals with advanced degrees Global Scale >10,000 clients, including >2,000 biopharma clients >150 sites in >20 countries Supported >80% of FDA-approved novel drugs over last three years (2020-22) Proven Results >95 preclinical candidates originated for clients since 1999 #1 position in Research Models, Safety Assessment & Microbial Solutions Charles River - JP Morgan Conference Presentation LTM 2022 revenue based on LTM September 2022 financial information. Diverse Revenue Base by Region 27% 5% $3.8B LTM 2022 revenue 68% ■North America ■Europe Asia-Pacific 4

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