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Investor Presentaiton

Investor Presentation First six months of 2018. Slide 56 Strengthened insulin volume market share in Region Latin America tMU 18 15 12 9 16 3 Latin America modern and new-generation insulin volume shares Latin America insulin market by segment Device penetration Modern insulin penetration CAGR volume¹: 11.1% Penetration CAGR value¹: 8.9% 60% 70% 60% Fast-acting 50% 40% Premix 40% 30% Long-acting 20% 20% 10% 0% 0% May 2013 May 2018 May 2013 0 - Novo Nordisk Eli Lilly Sanofi 43% 29% 15% May 2018 1 CAGR for 5-year period Note: IMS only covers the following 4 markets in Latin America (retail data): Argentina, Brazil, Colombia, Mexico Source: IQVIA monthly MAT data May, 2018 volume and value (DKK) figures MI: Modern insulin; NGI: New-generation insulin Note: Only top-3 shown Source: IQVIA monthly MAT data May, 2018 volume figures, numbers do not add up to 100% due to smaller insulin manufacturers not included MI: Modern insulin; NGI: New-generation insulin changing diabetes novo nordisk
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