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Reimagining Medicine

Company overview Financial review Conclusions Appendix References PluvictoⓇ continued strong performance with improving supply Sales evolution Global sales, USD m 80 00 Strong progress in Q2 GROWTH P PLUVICTO™ 240 Q2 sales of USD 240m, +14% USD vs. Q1 211 179 Millburn (US) and Zaragoza (EU) sites approved for commercial Pluvicto supply in April, continuing to ramp up gradually Actively starting new patients and onboarding new centers Ex-US reimbursement discussions ongoing Upcoming milestones PSMAfore pre-taxane data presentation and filing expected in H2 Submission and approval of Indianapolis site (US) 10 2 Q1 Q2 Q3 Q4 Q1 2022 2023 Q2 mCRPC metastatic castration-resistant prostate cancer. rPFS radiographic progression free survival. OS overall survival. 12 Investor Relations | Q2 2023 Results NOVARTIS | Reimagining Medicine
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