Investor Presentaiton

Targeted disease Medical Institution/ Isolation Period after Administration of GT products for Viral Shedding/Cartagena (2) Vector Gene Administration Isolation Cartagena Period Approval Method Sponsor HSV-TK Prostate cancer Kobe Univ. Hospital Bone 3 days 2005 metastases or Intra-prostatic Adeno HSV-TK Prostate Okayama Intra-prostatic 24 hours 2005 cancer Univ.Hospital Kitasato Univ. 2007 Hospital Sendai FGF-2 ASO / Berger's Kyushu Univ. Hospital disease Hindlimb. skeletal muscles 1 week 2006 AAV aromatic L- Late-stage Jichi Medical Intracerebral 72 hours 2006 amino acid Parkinson School decarboxylase disease Hospital

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