Q1'22 Financial Update

Balance sheet GBP million Variation Mar-22 Mar-21 Amount % Loans and advances to customers 221,741 223,104 (1,363) (0.6) Cash, central banks and credit institutions Debt instruments 57,781 5,583 56,291 1,491 2.6 7,861 (2,278) (29.0) Other financial assets 374 678 (304) (44.8) Other asset accounts Total assets 4,768 290,247 5,780 (1,012) 293,714 (3,467) (17.5) (1.2) Customer deposits Central banks and credit institutions Marketable debt securities 200,190 205,678 (5,488) 38,084 24,691 13,393 (2.7) 54.2 34,404 44,828 (10,424) (23.3) Other financial liabilities Other liabilities accounts Total liabilities Total equity 2,720 2,688 31 1.2 1,687 3,178 (1,491) (46.9) 277,085 281,063 (3,979) (1.4) 13,162 12,650 512 4.0 Other managed customer funds Mutual funds 7,207 7,192 15 0.2 7,207 7,112 94 1.3 Pension funds Santander Managed portfolios 80 60 (80) (100.0) + 24 14

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