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Investor Presentaiton

Biome Australia Key Product Research In a double-blind, randomised, placebo-controlled study across 5 years in over 300 subjects, the product formulation in Biome Lax was found to significantly improve the frequency of bowel movements, consistency of stool, ease of evacuation, sensation of complete emptying, and abdominal bloating compared to placebo (p < 0.001) after 30 days. Drago, L., Cioffi, L., Giuliano, M., Pane, M., Amoruso, A., Schiavetti, I., Reid, G., Ciprandi, G., & PROPAM Study Group. (2022). The Probiotics in Pediatric Asthma Management (PROPAM) Study in the Primary Care Setting: A Randomized, Controlled, Double-Blind Trial with Ligilactobacillus salivarius LS01 and Bifidobacterium breve B632 Journal of Immunology Research, 2022, 1-7. 6 5 4 3 2 NUMBER OF WEEKLY EVACUATIONS LEVEL OF DISCOMFORT ASSOCIATED WITH BOWEL MOVEMENTS 3 045 04 0.35 03 0.25 0.2 015 01 0.05 Baseline 15 days 30 days 0 Placebo Probiotic Basaline *p<0.001 compared to placebo Placebo Company Presentation | August 2023 IMPROVEMENT IN BLOATING 2.5 2 1.5 T 0.5 0 Baseline 15 days 30 days Placebo Probiotic 15 days - Probiotic 30 day *p = 0.007 compared to placebo "p<0.001 compared to placebo *p <0.001 compared to placebo Commercial in confidence
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