Ocuphire Pharma Investor Update slide image

Ocuphire Pharma Investor Update

RM Demand Side Validation TON LPED FECFD EDICEP ******** Bottom-Up Calculation of Annual Dilated Eye Exams ~100 M Annual Dilated Eye Exams are Performed in the US 32 Optometrists Number of Providers (X) 46,000 Ophthalmologists 18,000 Retina Specialists 3,000 Average Number of Weekly Exams (Y) 59 88 150 Estimated % Patients Dilated (Z) *IQVIA 2020 sales data; KOL Interview; GlobalData market research; and AOA Excel and Jobson Medical Information 'Bottom-Up Calculation' assumes 48 total work weeks in a year Supply side validation assumed each unit (bottle) has ~10 mL fill volume and each patient gets 2-4 drops 40% 50% 50% Total (X*Y*Z) * 48 wk/yr ~52 M -38 M ~10 M Supply Side Validation: Based on the ~2 million total units of mydriatic agents sold in 2020, we calculated the total number of dilated eye exams to be ~125 million patients, consistent with demand side estimates. 100M Annual Dilated Eye Exams Ocuphire PHARMA
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