BioNTech Investor Day Presentation Deck

Expanding global manufacturing footprint BIONTECH Gaithersburg Clinical-scale cell therapy -50 employees >45,000 square ft 930 As of June 2022. Marburg Commercial-scale mRNA ~750 employees >100,000 square ft Mainz Commercial-scale mRNA Individualized mRNA -200 employees -5,500 square ft Idar-Oberstein Clinical-scale cell therapy ~220 employees -30,000 square ft Senegal, Rwanda, & South Africa (planned for 2023) Modular mRNA BioNTainer 8 BONTAINER ⠀ Manufacturing and automation Construction and GMP licensure of new Mainz facility for iNeST 191 extiln Singapore (planned for 2023) Commercial-scale mRNA BIONTECH 49

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