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Reimagining Medicine

Company overview Financial review 2023 priorities Appendix New Novartis¹: Our focused strategy Focusing on high-value innovative medicines that alleviate society's greatest disease burdens through technology leadership in R&D and novel access approaches Our focus 5 core Therapeutic Areas² Cardiovascular, Immunology, Neuroscience, Solid Tumors, Hematology 2 + 3 technology platforms Chemistry, Biotherapeutics XRNA, Radioligand, Gene & Cell Therapy 4 priority geographies US, China, Germany, Japan STRATEGY Our priorities Accelerate growth Deliver returns Strengthen foundations Deliver high-value medicines (including launch excellence) Embed operational excellence Unleash the power of our people Scale data science and technology Build trust with society 1. New Novartis here and in the rest of the presentation refers to Novartis assuming planned Sandoz spin-off. Subject to final Novartis AG BoD and shareholder approval (EGM). 2. Other TAs opportunistically. 5 Investor Relations | Q4 2022 Results ✓ NOVARTIS | Reimagining Medicine
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