Novo Nordisk Annual Report 2021 slide image

Novo Nordisk Annual Report 2021

Contents Introducing Novo Nordisk Strategic Aspirations Key risks Management Consolidated statements Additional information. Novo Nordisk Annual Report 2021 29 O+ Patent status for marketed products The patent expiry dates for the products are shown in the table on the right. The dates provided are for expiry in the US, China, Japan and Europe of patents on the active ingredient, unless otherwise indicated, and include actual and estimated extensions of patent term, when applicable. For several products, in addition to the active ingredient patent, Novo Nordisk holds other patents on manufacturing processes, formulations or uses that may be relevant for exclusivity beyond the expiration of the active ingredient patent. Furthermore, regulatory data protection and/or orphan exclusivity may apply. Key marketed products in main markets (active ingredients) Diabetes: Human insulin and Modern insulins' Novo Norm (PrandinⓇ) VictozaⓇ9 Tresiba® RyzodegⓇ XultophyⓇ FiaspⓇ OzempicⓇ RybelsusⓇ Obesity: SaxendaⓇ WegovyⓇ Biopharm: Norditropin® (SimpleXxⓇ) Sogroya® NovoSevenⓇ NovoEight® NovoThirteenⓇ (TRETTEN®) Refixia (REBINYN®) Esperoct Vagifem 10 mcg US China Japan Europe³ Expired Expired Expired Expired Expired Expired Expired Expired 2023 Expired 2022 2023 2029 2024 2027 2028 2029 2024 2024² 2028 2029 2024 20242 2028 20303 2030³ 20303 20303 2032 2026 2031 2031 20324 20264 20314 20314 2023 2032 Expired 2026 Expired 2023 2031 2031 Expired 2034 Expired No patent Expired 2028 Expired 2031 Expired5 Expired 2036 Expired No patent Expired No patent No patent 2036 Expired No patent No patent No patent 2022 2027 2027 2032 2029 2034 2034 20226,7 No patent Expired Expired 1. Modern insulins are NovoRapid® (NovoLogⓇ), NovoMix® 30 (NovoLog® Mix 70/30) and Levemir® 2. Patent term extension until 2027 may apply 3. Formulation patent; active ingredient patent has expired 4. Tablet formulation and once-daily treatment regimen are protected by additional patents expiring in 2031-2034 5. Room temperature-stable formulation patent until 2023 in China, Japan and Germany and until 2025 in the US 6. Patent covers low-dose treatment regimen 7. Licensed to several generic manufacturers from October 2016 8. Patent status varies from country to country. The figures in the table are based on Germany 9. We have granted and pending patents covering the VictozaⓇ formulation. These patents generally expire in November 2024, except for the US where the formulation patent expires in February 2026
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