Investor Presentation - First Six Months of 2021

125 Investor presentation First six months of 2021 Novo NordiskⓇ Long-term value to society is driven by a strong sense of purpose and by being a responsible business Foundation ownership allows for long-term strategies, while still supporting agile responses to changing circumstances Novo Nordisk Foundation Financial, environmental and social responsibility anchored in Articles of Association and NNWay guides behaviour Socially responsible Institutional and private investors Novo Holdings A/S 76.8% of votes 28.3% of capital 23.2% of votes 71.7% of capital A shares 537 million shares Novo Nordisk A/S B shares 1,773 million shares Environmentally responsible Novo Nordisk Way Driving change to defeat diabetes and other serious chronic diseases Sustainable business Triple Bottom Line anchored in the Articles of Association in 2004 NN: Novo Nordisk. Note: In the Annual Report 2020 information on international standards, commitments and recommendations, which Novo Nordisk adheres to can be found. Note: Figures for votes and capital are as of 7 May 2021 Financially responsible

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