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Investor Presentaiton

121 Investor presentation Full year 2022 Region China at a glance. Million Diabetes trend Diabetes market by value and Novo Nordisk market share Region China Novo Nordisk reported sales DKK billion Full year 2022 Sales (mDKK) Growth² 200 30 100% 6% Total GLP-13 3,737 88% 14% 160 22 GLP-1 25 80% Long-acting insulin 1,636 -27% 86.8%¹ Premix insulin5 4,912 -13% 20 120 60% Fast-acting insulin 1,942 -21% Insulin 9.3%1 15 Human insulin 175 1,812 -38% 80 164 40% 141 10 10 Total insulin 10,302 -22% 40 40 Other Diabetes care? 1,181 -24% 5 9.9%1 20% OAD Diabetes care 15,220 -9% 0 2021 0 0% Obesity care 133 105% Nov 2030 2045 2017 Population with diabetes Diabetes growth rate -GLP-1 MS -Insulin MS Nov 2022 -OAD MS Diabetes & Obesity care 15,353 -9% Rare disease8 856 101% Total 16,209 -6% Source: International Diabetes Federation: Diabetes Atlas 10th Edition 2021 Region China covers Mainland China, Taiwan, and Hong Kong 1 CAGR calculated for last 5-year period Competitor insulin value market shares, as of Nov 2022: Novo Nordisk 52%, Sanofi 15%, Gan & Lee 0.1% and Eli Lilly 7%; Competitor GLP-1 value market shares, as of Nov 2022: Novo Nordisk 64% and Eli Lilly 29% OAD: Oral anti-diabetic; MS: Market Share; Source: IQVIA MAT, Nov 2022 value figures 4 2 At constant exchange rates; 3 Comprises VictozaⓇ and OzempicⓇ; Comprises Tresiba®, XultophyⓇ and Levemir®: 5 Comprises NovoMixⓇ and RyzodegⓇ: 6 Comprises NovoRapidⓇ; 7 Comprises Novo NormⓇ and needles; 8 Comprises SaxendaⓇ; 9 Comprises primarily Novo Seven®, Novo Eight® and NorditropinⓇ
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