Charles River - JP Morgan Conference Presentation slide image

Charles River - JP Morgan Conference Presentation

Multiple strategies to strengthen portfolio and enhance value for our clients and shareholders Disciplined M&A Strategic Partnerships Venture Capital Relationships M&A remains top, long-term priority for disciplined capital deployment and enhances growth strategy Invested >$4.5B in >25 acquisitions since 2012 Focused on enhancing breadth of scientific capabilities, expanding global scale, and maintaining leadership in advanced and emerging therapies Partnerships and licensing arrangements add innovative capabilities and cutting-edge technologies with limited upfront risk 19 active partnerships currently with >$110M invested to-date (1) • Highlights include: Valo Health - Discovery Al SAMDI Tech - Label-free high-throughput screening solutions Cypre - 3D tumor modeling PathoQuest - NGS sequencing Innovative strategy to establish CRL as a preferred partner to a large group of emerging, VC-backed biotech companies and create value ~10% of annual revenue comes from VC portfolio companies(2) Nearly 30% avg. annual return on VC relationships (investments and revenue)(3) (1) Charles River - JP Morgan Conference Presentation (2) (3) Amount invested in strategic partnerships excludes purchase price to acquire Distributed Bio. VC revenue includes VC firms with which we have invested, those which we have a strategic relationship, and other revenue from VC portfolio companies with which we have no formal relationship. Return calculation as of Oct. 2022 includes VC investment gains and operating cash flow from revenue generated from VC funds in which we have invested (both net of tax). It does not include revenue generated from VC funds in which we have not invested. 21
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