Charles River - JP Morgan Conference Presentation

Our commitment to Corporate Citizenship Leadership Operating our business with integrity and accountability - - - 36% women or minority representation on Board Adopted proxy access in 2021 Formalized and launched ESG Council, chaired by COO Humane Care Initiative: 3R principles of Replacement, Reduction and Refinement Published formal Human Rights statement aligned with U.N. principles - - - People Creating a work environment built on trust, inclusion, accountability, respect, and well-being 9 global Employee Resource Groups (ERGS) with >2,000 employees Demonstrate equitable pay practices, with less than 1% gap in pay by gender (global) and race/ethnicity (U.S.) Provide employee sabbaticals and additional development opportunities Employees completed nearly 290,000+ development courses in 2021 יויו 金剑 Communities Supporting and investing in the geographies where we live and work ☑Environment Embedding working safely and sustainably into everything we do - - Established Charles River Employee Relief Fund in 2021 Launched Charitable Match Policy, with 1:1 company match of employee charitable donations Employees volunteered a collective 13,000+ hours of service in 2021 Donated 500 STEM boxes for youth in foster care during first annual STEM Day - - Funded $4.5M capital projects in 2021 under the Sustainability Capital Fund Goal to reduce annual GHG emissions ~3.2% Achieved 25% reduction in global Scope 1 & 2 GHG emissions from 2018 to 2021 Committed to achieving 100% renewable electricity by end of 2023 through vPPAs in North America (solar) and Europe (wind) Charles River - JP Morgan Conference Presentation 22 222

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