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Investor Presentaiton

Q2 2023 JARDIANCE SALES INCREASED 45% Millions U.S. sales increased 54% International sales increased 34% $419 $578 $461 Q1 Q2 Not for promotional use Lilly U.S. TRX SOM and Market Volume 63% 580 Jardiance1 $668 $612 $573 540 62% 500 13 WK RA TRX SOM 61% Market 460 420 60% 380 340 59% 300 58% 260 Q3 Q4 Jun Sep Dec Mar Jun 2021 2021 2021 2022 2022 Sep 2022 Dec Mar Jun 2022 2023 2023 2022 2023 Source: IQVIA NPA TRX 3MMA, weekly data June 30, 2023; RA = rolling average Jardiance is part of Lilly's alliance with Boehringer Ingelheim. 1 Jardiance includes Glyxambi and Synjardy 2023 Q2 EARNINGS 13 WK RA TRx Market Volume (000s) 31

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