Investor Presentation Full Year 2021

81 Investor presentation Full year 2021 Novo Nordisk's ambition within cardiovascular disease In-licensing/acquisition of mid-stage assets CORVIDIA Can of prothena License agreement/partnership Heartseed Accelerate internal pipeline Subcutaneous PCSK9i - successful phase 1 results At least one product launched between 2024-2028 targeting atherosclerotic cardiovascular disease or heart failure with a highly innovative, first to market product serving a significant unmet need in a large patient population Novo NordiskⓇ

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