Ocuphire Pharma Investor Day Presentation Deck

RM 54 MIRA-2: Mean Pupil Size Over Time After Maximum Pupil Dilation Nyxol Treatment Significantly Reduced PD Starting at 1 Hour Post-Dose through 24 Hours Mean Pupil Diameter (mm) 8 7 5 Mydriatic 4 3 -1 Max pupil dilation Nyxol Reduced PD Faster Across All Mydriatic Agents* Study Eye Mean Pupil Diameter Treatment Administered 0 0.5 p<0.0001 1 11 p<0.0001 p<0.0001 MIRA-2 Phase 3 Trial 2 p<0.0001 3 p<0.0001 4 5 Time Post-Treatment with Nyxol/Placebo (Hours) Source: MIRA-2 TLR table # 14.2.2.1 (mITT). Standard Error bars are shown. *Data includes three of the most common mydriatics used in practice (Phenylephrine, Tropicamide, Paremyd) p<0.0001 6 Nyxol n=94 Placebo n=91 p<0.0001 24 Ocuphire PHARMA

View entire presentation