Q1 2022 Results slide image

Q1 2022 Results

Company overview Financial review 2022 priorities Appendix References 2022 events¹ (expected) 3 INNOVATION ✓ Achieved NME Lead Regulatory H1 Pluvicto™ mCRPC (US/EU) decisions H1 VijoiceⓇ PROS (US) H2 ScemblixⓇ 3L CML (JP/EU) H2 tislelizumab ESCC 2L (US) Readout not supportive × Missed Other readouts H1 sabatolimab HR-MDS Ph2 H1 CosentyxⓇ Lichen planus Ph2 PRELUDE H1 CosentyxⓇ axSpA IV Ph3 INVIGORATE-1 H1 icenticaftor COPD Ph2b Submissions H1 H2 H1/H2 JakaviⓇ acute & chronic GVHD (EU /JP) H1/H2 KymriahⓇ r/r follicular lymphoma (US/EU/JP) H1/H2 BeovuⓇ DME (US/EU ✓/JP) ensovibep COVID-19 (US ✓) H1/H2 Cosentyx® HS (EU/US) H1/H2 tislelizumab NSCLC (EU/US) tislelizumab 1L Nasopharyngeal cancer (US) H2 UNR844 presbyopia Ph2 READER Ph3/pivotal study starts H1 CosentyxⓇ peripheral SpA H1 OAV101 SMA IT STEER ✔ H1 ensovibep COVID-19 (EMPATHY Part B) H2 JDQ443 NSCLC mono H2 ianalumab Sjögren's Syndrome H2 ianalumab Lupus Nephritis H2 CosentyxⓇ Psoriatic Arthritis IV (US) H2 ociperlimab solid tumors Submissions- H2 canakinumab NSCLC Ph3 Canopy A H2 TM Pluvicto nmCRPC enabling H2 iptacopan PNH Ph3 APPLY-PNH H2 YTB323 2L DLBCL readouts H2 KisqaliⓇ HR+/HER2- BC (adj) Ph3 NATALEE (event driven now moving to 2023) H2 OAV101 SMA IT Ph3b STRENGTH H2 lutetium (177Lu) vipivotide tetraxetan mCRPC1, pre-taxane Ph3 PSMAfore² 1. Selected. 2. Could move to early 2023. 20 Investor Relations | Q1 2022 Results 1 NOVARTIS | Reimagining Medicine
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