Retail Banking Performance Update

United Kingdom (Constant EUR mn) Change Change Q1'21 Q2'21 Q3'21 Q4'21 Q1'22 Net interest income 1,013 1,100 1,160 1,145 1,170 1,220 Q2'22 Q3'22 1,281 Q4'22 Q4'22/Q3'22 2021 2022 2022/2021 1,322 +3.2% 4,419 4,992 +13.0% Net fee income 123 119 114 81 90 109 94 97 +3.4% 437 390 -10.8% Gains (losses) on financial transactions and other (10) (6) 21 (7) 7 6 28 (4) (2) 36 Total revenue 1,126 1,213 1,296 1,219 1,267 1,335 1,402 1,414 +0.9% 4,854 5,418 +11.6% Operating expenses (668) (655) (639) (651) (659) (673) (662) (691) +4.3% (2,613) (2,685) +2.8% Net operating income 458 558 657 568 608 662 740 724 -2.2% 2,242 2,733 +21.9% Net loan-loss provisions (19) 88 (2) 179 (50) (73) (109) (83) -23.8% 247 (316) Other gains (losses) and provisions (32) (63) (39) (188) (65) (99) (89) (266) +199.6% (322) (517) +60.7% Underlying profit before tax 408 583 616 560 493 490 542 375 -30.8% 2,167 1,900 -12.3% Underlying consolidated profit 293 396 446 415 368 359 403 264 -34.6% 1,549 1,395 -10.0% Underlying attributable profit 293 396 446 415 368 359 403 264 -34.6% 1,549 1,395 -10.0% Santander 28

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