Investor Presentation - First Six Months of 2021

100 Investor presentation First six months of 2021 Insulin market size and volume share of growth and market share in Region China China Insulin market share and market size (DKK billion) Market growth A Market share Insulin volume: market share 80% 50% 48% 13 12% +1.6% Total 21% Long- acting 80% Fast- 2 acting Premix 79% 4 41% Human 3 5 Novo Nordisk Competitors Source: IQVIA, May 2021, LHS graph - Value, RHS Graph - Volume, MAT; NN: Novo Nordisk 57% 40% 60% 18% +5.4% 51% 30% 40% 20% 16% -0.0% 20% 7% 10% 12% +1.6% 0% May NN market share 2018 0% -2.6% 0% May 2021 NN share of growth Market growth (right axis) NN growth (right axis)

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